Post-Doctoral Reseacher in Functional Genomics

Updated: about 2 months ago
Job Type: FullTime
Deadline: 08 Sep 2022

The University of Helsinki is an international scientific community of 40,000 students and researchers. It is one of the leading multidisciplinary research universities and ranks among the top 100 international universities in the world.

We are an equal opportunity employer and offer an attractive and diverse workplace in an inspiring environment with a variety of development opportunities and benefits.

The Faculty of Biological and Environmental Sciences is Finland’s most high-profile and extensive hub of research and teaching in the field. The Faculty educates experts to meet the needs of universities, research institutes, government, schools and the business sector.

A 3 year post-doctoral position is available at the University of Helsinki, Finland to work in Prof. Craig Primmer’s research group (http://www.helsinki.fi/evolution-conservation-and-genomics  ). The position is a part of an ERC-funded Advanced Grant entitled “Life history genes in fishes: bridging functional and evolutionary genetics for understanding life history trait evolution”. This post-doc will focus on understanding the molecular mechanisms of large effect loci associated with life-history traits in 3 fish species fishes (e.g. Barson et al. 2015; Pearse et al. 2019; Verta et al. 2020; Ahi et al. 2022; Matschiner et al. 2022).

The post-doc will be responsible for conducting and co-supervising research within the project using genomic, cellular and/or physiological approaches to understand how the candidate genes, and genes they interact with, influence life-history phenotypes in the species of interest. The project could involve aspects of any of the following; qPCR, ddPCR, RNAseq, gene co-regulation inference, single cell RNA-seq, CRISPR/Cas9 gene editing, Tol2-mediated reporter assays etc. Tissue samples from developmental time series are already available for some gene-species combinations, but collection of additional material will also be a central part of the work, as is molecular methodological development. This work is complemented by molecular, ecological, evolutionary and quantitative genetic research being conducted within the same and related projects by others in the group.

An appointee to the position shall hold a doctoral degree and have the ability to conduct independent scholarly work. Suitable applicants will have a strong background in functional genomics or molecular biology in any species as demonstrated by publications in relevant fields and will show an interest in developing and applying the most recent functional genomics approaches in Atlantic salmon. Experience with e.g. gene expression analysis, methodologies used in genome editing and reporter assays, single-cell sequencing, lipidomics, metabolomics, transcriptomics or proteomics, is advantageous, as is knowledge of bioinformatics and an interest in evolutionary biology. The ability to work as a part of a larger research team addressing related questions is also important.

Informal inquiries can be directed to Professor Craig Primmer (craig.primmer@helsinki.fi ).

Formal applications should include:

  • a CV including a list of publications and with names and contact details of at least two referees
  • a max. 2-page letter of motivation

To apply, please submit your application using the University of Helsinki electronic recruitment system by clicking on “Apply for job” via https://www.helsinki.fi/en/open-positions

The deadline for applications is Thursday September 8, 2022. The positions is available immediately, but a start date up to the early months of 2023 may be considered (although an earlier start is preferred).

The positions are initially available until 12/2025, but a 1-2 year extension may be possible. The salary will be based on level 5 of the demands level chart for teaching and research personnel in the salary system of Finnish universities. In addition, the appointee will be paid a salary component based on personal performance with the overall starting salary amounting to c. 3200-3600 EUR per month, depending on the previous relevant research experience of the candidate.

Finland is a member of the EU, has high quality free schooling (also in English), very affordable childcare, generous family benefits and healthcare, and has been ranked as the world’s happiest country three years running and the best country in the world for expat families. The University of Helsinki is a top 100 ranked university in most ranking lists, and is currently investing heavily in life science research (see https://www.helsinki.fi/en/helsinki-institute-of-life-science ) and the City of Helsinki is in the world’s top ten most livable cities. Primmer’s research group currently consists of 4 post docs, 7 PhD students and 3 research assistants with 11 different nationalities. The fish biology research field has traditionally lacked diversity, but the group is committed to helping to influence a change and we therefore strongly encourage applications from researchers with diverse backgrounds, beliefs and talents. Successful applicants are expected to adhere to the university and research group’s codes of conduct.

Relevant articles:

  • Ahi et al. (2022). Strong regulatory effects of vgll3 genotype on reproductive axis gene expression in juvenile male Atlantic salmon. General and Comparative Endocrinology 325, 114055.
  • Barson et al. (2015) Sex-dependent dominance at a single locus maintains variation in age at maturity in salmon. Nature 528,405–408.
  • Matschiner et al (2022). Supergene origin and maintenance in Atlantic cod. Nature Ecology & Evolution, 6, 469–481
  • Pearse et al. (2019). Sex-dependent dominance maintains migration supergene in rainbow trout. Nature Ecology and Evolution 3, 1731–1742.
  • Verta et al. (2019). Cis-regulatory differences in isoform expression associate with life history strategy variation in Atlantic salmon. PLOS Genetics 16, e1009055.

View or Apply

Similar Positions