PDRA in Peptide Therapeutics in collaboration with Bicycle Therapeutics (Fixed Term)

Fixed-term: The funds for this post are available for 30 months in the first instance.

Available: from March 2024

A unique opportunity for a successful applicant to undertake research at the intersection of academia and industry to develop novel imaging technologies using bicyclic peptides. The UKRI Innovate UK funded Knowledge Transfer Partnership (KTP) is a collaboration between Cambridge University and Bicycle Therapeutics (BicycleTx).

Based at BicycleTx, Cambridge UK, in collaboration with the Spring Group at the University of Cambridge, the successful applicant will contribute to achieve the KTP's objectives to develop and transfer knowledge as well as techniques required to develop new imaging technologies.

The KTP Associate will be an employee of the University of Cambridge but will spend most of their working time at BicycleTx`s premises at Granta Park, Great Abington, Cambridge, CB21 6GS and when required at the University of Cambridge. The contract is a fixed term for a duration of 30 months.

Qualifications PhD (or final stages of completion) in Chemistry, Biochemistry or closely related field

Key Tasks:

• On boarding, familiarisation with the company and university
• Creation of a detailed plan and complete a mini project
• Design, synthesis, purification and analysis of chemically modified bicyclic peptides
• Phage display using BicycleTx's proprietary technology
• Assay development and implementation
• Determination of pharmacokinetic parameters
• Disseminate and embed developed knowledge within BicycleTx to various stakeholders throughout the KTP via reports, presentations, group discussions, workshops and staff training
• Present findings to stakeholders prepare and complete full documentation
• Disseminate research via scientific publications and conferences

Benefits:

• Develop managerial skills and attend two residential managerial workshops
• £5,000 personal training budget (total)
• The opportunity to lead a project, develop project management skills and improve long term career prospects
• Mentoring by industry experts, world-class academics and a Knowledge Transfer Network Adviser
• Access to state-of-the-art research facilities
• Access to a full range of continuing professional development modules within the University and bespoke training packages via BicycleTx's personal development framework
• Gain experience in drug discovery working at the intersection of academia and industry
• Ability to work in a largely self-determined way, across the industry-academic partnership

Bicycle Therapeutics (NASDAQ: BCYC) is a clinical-stage biopharmaceutical company developing a novel class of medicines. Our pipeline includes Bicycle Toxin Conjugates® as well as fully synthetic Bicycle® systemic immune cell agonists and Bicycle tumour-targeted immune cell agonists (Bicycle TICAs) focused on oncology indications with high unmet medical need. Bicycle is headquartered in Cambridge, UK, and our US operations run out of Cambridge, MA.

Culture is key and all BicycleTx employees actively embrace and role model our company values:

• We are adventurous. We believe it is the way to deliver extraordinary results for our patients.
• We are dedicated to our mission. You cannot change the world if you do not have determination.
• We are one team. We only succeed when we work together.

For further details about Knowledge Transfer Partnerships please visit http://www.ktp-uk.org/

For further details please visit https://www.bicycletherapeutics.com or https://www-spring.ch.cam.ac.uk/

Appointment at the Research Associate level is dependent on the award of a PhD. Those who have submitted but not yet received their PhD will be appointed at the Research Assistant level, which will be amended to Research Associate once the award of the PhD has been confirmed. The salary range for a Research Associate is £36,024-£44,263 pa.

Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.

Please ensure that you upload your Curriculum Vitae (CV), a covering letter and publications list in the upload section of the online application. If you upload any additional documents that have not been requested, we will not be able to consider these as part of your application.

For informal enquiries, please contact Professor David Spring [email protected]

Please quote reference MA39659 on your application and in any correspondence about this vacancy.

The Department holds an Athena SWAN silver award for women in Science, Technology, Engineering, Mathematics, and Medicine.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Further information
Apply online