MRC Postdoctoral Scientist in Bioinformatics / Computational Biology

3 Years fixed term

Salary: £32,302 - £35,143 plus London allowances (£3,727 & £1,402) per annum

London, UK

Applications are invited for a 3-year post-doctoral research position in Cardiovascular Genomics and Precision Medicine at Imperial College London. The research group spans the MRC London Institute of Medical Sciences (LMS) and National Heart and Lung Institute at Imperial College London, and the Cardiovascular Division of Royal Brompton & Harefield Hospitals. The post will be primarily based at the LMS on the Hammersmith Hospital campus, which provides an outstanding environment for interdisciplinary research with excellent core support. For a description of the institute and details of core facilities, visit www.lms.mrc.ac.uk . The LMS is adjacent to Imperial College’s National Heart & Lung Institute and the British Heart Foundation Centre of Research Excellence, providing a critical mass of expertise at the cutting edge of cardiovascular and genomic science.

We are looking for a talented computational biologist, with experience in human genetics (preferably including both common and rare disease genetics), to join our Cardiovascular Genetics & Genomics team. Our research is aimed at understanding the genetic basis of cardiovascular disease, with a focus on inherited heart muscle diseases. The post-holder will be embedded in a well-established bioinformatics team and will use genomic data (whole genome sequencing / targeted sequencing / SNP array) to study the genetic architecture of inherited cardiomyopathies in human populations.

Applicants will have a PhD in computational biology, statistical genetics, or a closely related discipline, or equivalent research, industrial or commercial experience, and will be skilled in bioinformatics. The successful applicant will join a vibrant group, led by Dr James Ware. The group has a track record of excellence and innovation in cardiovascular genetics and computational genomics, with numerous publications in top-tier journals and extensive international collaboration (e.g. de Marvao et al JACC 2021; Tadros et al Nat Genet 2021; Karczewski et al Nature 2020; Whiffin et al Nat Comms 2020).

This is an MRC Postdoctoral Scientist position providing training and development supporting post-doctoral scientists in early or changed career paths helping to establish them as successful research scientists in their chosen field. We offer a highly attractive benefits package including generous pension scheme.

Informal enquiries should be sent to [email protected]

For full details of this post and to complete an online application at https://mrc.tal.net/vx/lang-en-GB/appcentre-1/candidate/postings/1789 and upload your CV, a brief cover letter (describing research interests and motivation for the position) and the names and contact information of 2 academic references. Please do not send reference letters at this stage.

Please quote reference number LMS 1738

Closing date: 7th January 2022

Final appointment will be subject to pre-employment screening.

*Additional allowances comprise a £1,000 lump sum Settlement Allowance plus a yearly Training Allowance of £850 in the first year, paid in monthly instalments. The Training Allowance increases to £1,300 in year two, and £1,800 in the third year.

Choosing to come to work at the MRC (part of UKRI) means that you will have access to a host of benefits from a defined benefit pension scheme and excellent holiday entitlement to access to employee shopping/travel discounts and salary sacrifice cycle to work scheme, plus the chance to put the MRC and UKRI on your CV in the future.
The MRC London Institute of Medical Sciences is a research institute within UK Research and Innovation. UK Research and Innovation is a new entity that brings together nine partners to create an independent organisation with a strong voice for research and innovation, more information can be found at www.ukri.org