Laboratory Technician - MLC 1530

Updated: 28 days ago
Location: Harwell, ENGLAND
Deadline: 25 Apr 2021

View Vacancy -- Laboratory Technician - MLC 1530
Open Date
06/04/2021, 17:00
Close Date
25/04/2021, 23:55

MRC Mary Lyon Centre

MRC Harwell Institute is an international biological research centre at the forefront of the use of mammalian models to study genetics and human diseases. Located on the Harwell Campus, just south of Oxford, it is nestled amongst a vibrant community of leading science organisations. We aim to advance medicine through cutting-edge research into the genetic basis of disease. Our research programmes span an entire lifetime, from embryonic development to diseases of ageing. There are over 300 staff at the Institute made up of research scientists, technicians, animal carers, and business support personnel.



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MRC - 5

Harwell Campus, Oxfordshire

£25,798 - £27,501 (depending on experience)


Fixed Term

Technical & Scientific Professionals

Full Time

Until 31st March 2022

Overall purpose:

The Biological Resources Group (BRG) is responsible for the MRC-Harwell's embryo bank, which currently holds >3,000 mouse stocks and is internationally recognised as one of the largest sources of mouse models of human disease in the world. We are also founding partners of the European Mutant Mouse Archive (EMMA: which underpins mouse cryopreservation services for the wider European community. The Mary Lyon Centre (MLC) is located on the Harwell Campus which is an thriving science hub, specialising in Health, Space and Energy based technologies (


We currently have a vacancy for a laboratory technician. This is a fixed term appointment ending on the 31st Mar 2022, in the first instance. This role will revolve around the cryopreservation of mouse models of human disease generated at Harwell, or by the wider scientific community. In response to specific requests the post-holder will be asked to recover mutant lines from the archive using in vitro fertilisation and embryo transfer techniques.


The ideal candidate will need a sound understanding of mammalian biology, good communication skills and be computer literate. Previous experience of cryo-preservation would be desirable but training will be given.


This is a great opportunity for someone with an interest in reproductive biology to acquire a solid grounding in assisted reproduction technologies and we encourage anyone with aspirations in this area to apply.


Main duties / key responsibilities:


Main duties and responsibilities will depend on previous experience but will centre on:

Setting up and executing in vitro fertilisation sessions

Dissecting mouse tissues and embryo/sperm harvesting

Cryopreserving embryos, spermatozoa and ovarian tissue

Carrying out the duties expected of a Home Office Personal Licence holder

Updating archive records

Sample management/tracking

Media preparation

Following SOP’s and working to ISO 9001 standards

Maintaining the biosecurity of the MLC and MLC Quarantine suite

Assisting with the routine laboratory activities

The post will involve some out of hours working


Working relationships:

The post holder will report directly to the laboratory manager and will work closely with staff from the Mary Lyon Centre’s Operations team. The post holder may also be expected to liaise closely with the wider scientific community.

Equality & Diversity

The MRC values the diverse skills and experience of its employees and is committed to achieving equality of treatment for all. Our objectives are that all individuals shall have equal opportunities for employment and advancement on the basis of their skills, aptitudes and abilities. The MRC is committed to the engagement and retention of the best possible talent and to creating an environment that encourages excellence in scientific research through good equalities and diversity leadership and management.


Corporate/Local responsibilities & requirements

The job holder must at all times carry out their responsibilities with due regard to the MRC’s:

  • Code of Conduct
  • Equality and Diversity policy
  • Health and Safety policy
  • Data Protection and Security policy


Job descriptions should be reviewed on a regular basis and at the annual appraisal.   Any changes should be made and agreed between the post holder and their manager.


The above lists are not exhaustive and the job holder is required to undertake such duties as may reasonably be requested within the scope of the post.   All employees are required to act professionally, co-operatively and flexibly in line with the requirements of the post and the MRC.



Education / Qualifications / Training required:


Higher education/further education qualification in biological science.



BSc/MSc in reproductive biology. Home Office Licence PIL A-C.


Previous work experience required:


Previous experience of a laboratory environment and/or working with laboratory animals.


Experience of working within the area of reproductive biology. Experience of working in a high throughput service role.


Knowledge and experience:


Laboratory skills:

A background in biology with previous experience of working in a laboratory setting.

Computer literacy:

High level of computer literacy.

Team work:

Ability to work within a multi-disciplinary team.

Communication skills:

Good verbal and written communication skills.

Attention to detail:

Keen eye for detail and a desire to master a range of laboratory techniques.

Organisational skills:

Ability to work independently and prioritise weekly work schedule.

Flexible working:

Ability to work within various work environments as the requirements of the clients change.

Quality control:

Ability to follow SOP’s and produce work of a high standard.



Laboratory skills:

Previous experience of pre-implantation embryo culture work, cryopreservation of mammalian embryos/germplasm or experience of other cell systems and/or organ cultures.

Computer literacy:

Familiarity with data management and on-line database tools.

Team work:

As above but with the proven ability to think and work independently.

Communication skills:

Previous experience of communicating with members of other laboratories within the UK and abroad.

Attention to detail:

As above but with the proven ability to trouble-shoot problems when things go wrong.

Organisational skills:

Proven history of good time management in a high throughput service environment.

Flexible working:

Previous experience of working out of hours/flexible working patterns.

Quality control:

Proven experience of working to ISO9001 standards, or equivalent.


Personal skills/behaviours/qualities:


Good interpersonal and time management skills. The post holder will be working with a team of laboratory technicians and may be required to communicate with the wider scientific community. It is essential that the post holder has a customer focused approach to service delivery.



A self-motivated, confident and outgoing personality.


Closing date for applications is Sunday 25th April 2021.

Interviews will be held w/c 4th May 2021.

The MRC is a great place to work and progress your career, be it in scientific research or the support functions.The MRC is a unique working environment where our researchers are rewarded by world class innovation and collaboration opportunities that the MRC name brings. The MRC is an excellent place to develop yourself further and a range of training & development opportunities will be available to you, including professional registration with the Science Council.
Choosing to come to work at the MRC (part of UKRI) means that you will have access to a whole host of benefits from a defined benefit pension scheme and excellent holiday entitlement to access to employee shopping/travel discounts and salary sacrifice cycle to work scheme, as well as the chance to put the MRC and UKRI on your CV in the future.
Our success is dependent upon our ability to embrace diversity and draw on the skills, understanding and experience of all our people. We welcome applications from all sections of the community irrespective of gender, race, ethnic or national origin, religion or belief, sexual orientation, disability or age. As "Disability Confident" employers, we guarantee to interview all applicants with disabilities who meet the minimum criteria for the vacancy.
UKRI supports research in areas that include animal health, agriculture and food security, and bioscience for health which includes research on animals, genetic modification and stem cell research. Whilst you may not have direct involvement in this type of research, you should consider whether this conflicts with your personal values or beliefs.
We will conduct a full and comprehensive pre-employment check as an essential part of the recruitment process on all individuals that are offered a position with UKRI. This will include a security check and an extreme organisations affiliation check.

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