Laboratory and Phenotyping Technician - MLC 1520

Updated: 19 days ago
Location: Harwell, ENGLAND
Deadline: 21 Apr 2021

View Vacancy -- Laboratory and Phenotyping Technician - MLC 1520
Open Date
24/03/2021, 15:00
Close Date
21/04/2021, 23:55

MRC Harwell Institute

 MRC Harwell Institute is an international biological research centre at the forefront of the use of mammalian models to study genetics and human diseases. Located on the Harwell Campus, just south of Oxford, it is nestled amongst a vibrant community of leading science organisations. We aim to advance medicine through cutting-edge research into the genetic basis of disease. Our research programmes span an entire lifetime, from embryonic development to diseases of ageing. There are over 300 staff at the Institute made up of research scientists, technicians, animal carers, and business support personnel.
UK Research and Innovation is a new entity that brings together nine partners to create an independent organisation with a strong voice for research and innovation, more information can be found at

MRC - 5

Harwell Campus, Oxfordshire

£25,798 per annum


Technical & Scientific Professionals

Full Time

Overall purpose:

To provide a cross team service in the clinical pathology lab, undertaking Haematology, Clinical Chemistry analysis and plate based assays as well as a range of phenotyping assays performed on live mice as part of the Phenotyping service at the Mary Lyon Centre. The Phenotyping team at the Mary Lyon Centre are a team of dedicated individuals, working together to understand how changes in genes effect behaviour, metabolism and sensory systems in mice. Data produced by this team informs researchers around the UK and across the world about the roles of many mammalian genes and how they might lead to disease in humans.


Main duties / key responsibilities:  

Clinical Chemistry

  • Care and operation of all equipment including Beckman Coulter AU680, Advia2120, FLUOstar Optima plate reader and RAPID Lab 348EX blood gas analyser.
  • Processing of samples for analysis.


In-vivo phenotyping

  • Carry out in-vivo phenotyping assays such as blood sampling, recording metabolic activity and body composition measurements in mice.
  • Work under the Animals (Scientific Procedure) Act 1986 to ensure high standards of animal care and welfare whilst carrying out scientific procedures.


Time management

  • Sensible management of scheduled work to effectively prioritise work and maintain good turn-around times.
  • Cross team working.


Quality Assurance & Record Keeping

  • Ensuring that all SOP’s, risk assessments and COSHH are observed.
  • Maintenance of database and keeping various records and logs up to date as per requirements for ISO 9001 certification.


Data Collection & Analysis

  • Collating, recording and uploading data into LIMS databases, spreadsheets and programs appropriate for data capture.
  • Downloading, collating and performing critical quality control analysis on phenotyping data.


Working relationships:  

The post holder will report to the Metabolic Phenotyping Manager, working within the clinical chemistry laboratory and a team of phenotyping animal technicians. They will liaise with internal and external customers as well as service engineers and suppliers.

Equality & Diversity

The MRC values the diverse skills and experience of its employees and is committed to achieving equality of treatment for all. Our objectives are that all individuals shall have equal opportunities for employment and advancement on the basis of their skills, aptitudes and abilities. The MRC is committed to the engagement and retention of the best possible talent and to creating an environment that encourages excellence in scientific research through good equalities and diversity leadership and management.


Corporate/Local responsibilities & requirements

The job holder must at all times carry out   their responsibilities with due regard to the MRC’s:

  • Code of Conduct
  • Equality and Diversity policy
  • Health and Safety policy
  • Data Protection and Security policy


Job descriptions should be reviewed on a regular basis and at the annual appraisal. Any changes should be made and agreed between the post holder and their manager.


The above lists are not exhaustive and the job holder is required to undertake such duties as may reasonably be requested within the scope of the post. All employees are required to act professionally, co-operatively and flexibly in line with the requirements of the post and the MRC.



Education /   Qualifications / Training required:


  • A levels or equivalent in Biological or Biomedical Sciences



  • Home Office licence
  • Relevant BSc in Biological or Biomedical Sciences


Previous work experience required:


  • General laboratory experience
  • Experience handling blood samples and running semi-automated analysers



  • Experience in clinical chemistry, haematology, ELISA or other immunoassays
  • Experience performing metabolic phenotyping tests in mice
  • Experience of working in a commercial or service led environment
  • Experience working under the Animals (Scientific Procedures) Act 1986


Knowledge and experience:


  • Computer Literacy
  • Ability to accurately follow protocols/SOPs



  • Experience with laboratory information management systems
  • Experience writing SOP’s
  • Experience handling complex datasets
  • Experience in phenotyping procedures


Personal skills/behaviours/qualities:


  • Excellent communication skills
  • Excellent attention to detail
  • Flexible and adaptable in approach to work to ensure changing priorities and deadlines are met
  • A service delivery focus
  • Ability to work on day to day functions both independently and as part of a team
  • Acute attention to detail.



  • Experience in training others


The candidate may occasionally be required to travel to attend meetings or training

Contracted to work 36 hours per week

Overtime will be required at weekends on a rota basis (usually 8-11am every fourth weekend)

Support will be provided towards professional registration with the Science Council

The MRC is a great place to work and progress your career, be it in scientific research or the support functions.The MRC is a unique working environment where our researchers are rewarded by world class innovation and collaboration opportunities that the MRC name brings. The MRC is an excellent place to develop yourself further and a range of training & development opportunities will be available to you, including professional registration with the Science Council.
Choosing to come to work at the MRC (part of UKRI) means that you will have access to a whole host of benefits from a defined benefit pension scheme and excellent holiday entitlement to access to employee shopping/travel discounts and salary sacrifice cycle to work scheme, as well as the chance to put the MRC and UKRI on your CV in the future.
Our success is dependent upon our ability to embrace diversity and draw on the skills, understanding and experience of all our people. We welcome applications from all sections of the community irrespective of gender, race, ethnic or national origin, religion or belief, sexual orientation, disability or age. As "Disability Confident" employers, we guarantee to interview all applicants with disabilities who meet the minimum criteria for the vacancy.
UKRI supports research in areas that include animal health, agriculture and food security, and bioscience for health which includes research on animals, genetic modification and stem cell research. Whilst you may not have direct involvement in this type of research, you should consider whether this conflicts with your personal values or beliefs.
We will conduct a full and comprehensive pre-employment check as an essential part of the recruitment process on all individuals that are offered a position with UKRI. This will include a security check and an extreme organisations affiliation check.

View or Apply

Similar Positions