CDF / Postdoctoral Scientist

Updated: 3 months ago
Location: Cambridge, ENGLAND
Job Type: FullTime
Deadline: 20 Dec 2020

CDF / Postdoctoral Scientist

Salary Range £31,602 to £34,443 per annum

Fixed-term, 3 years

MRC Laboratory of Molecular Biology, Cambridge, UK

An opportunity is available for a Postdoctoral Scientist to join the group of Dr Jing Ren at the MRC Laboratory of Molecular Biology (LMB) to investigate how the serotonin system is assembled during development, and the consequences when it is disrupted.

We have revealed that the serotonin system within individual raphe nucleus contains parallel serotonin sub-systems, which lays the foundation for integrating anatomical, neurochemical, physiological, and behavioural functions of the serotonin system. We work to bridge the gap between the molecular mechanisms of developmental assembly and the behavioural functions of serotonin neurons.

We are looking for a highly motivated individual who will thrive in a friendly and supportive group. This position will focus on studying the molecular machinery controlling serotonin terminal specification by firstly proteomic profiling for cell surface molecules of serotonin terminals during development, and exam the consequences when the signalling pathway is disrupted by whole-brain axon projection imaging and in vitro assay development of organotypic culture system.

Candidates with advanced microscopy imaging (light sheet, confocal, two-photon, or super-sesolution), primary culture and ES cell/organoid culture training are highly desired. Candidates have experience in proteomics and mouse brain stereotactic surgery are highly encouraged to apply.

The MRC LMB provides an unsurpassed environment for early-career Researchers, including an international, collaborative community, training and mentoring programmes for career development and world-class core facilities. In addition, the MRC provides excellent healthcare and social benefits.

The successful applicant will be awarded a 3-year Career Development Fellowship / Postdoctoral Training Scheme position.  This is a training and development position for a post-doctoral scientist who has recently completed their doctoral studies, is moving into a new research discipline or has limited experience of key transferable skills. The MRC LMB has excellent scientific core facilities and training opportunities.

Informal enquiries can be made to Dr Jing Ren at jren">mailto:jren@mrc-lmb.cam.ac.uk">jren @mrc-lmb.cam.ac.uk and more information about the group can be found here https://www2.mrc-lmb.cam.ac.uk/groups/ren/ ">https://www2.mrc-lmb.cam.ac.uk/groups/ren/">https://www2.mrc-lmb.cam.ac..... Additional information about the Neurobiology Division and the laboratory as a whole can be found at http://www.mrc-lmb.cam.ac.uk .

">http://www.mrc-lmb.cam.ac.uk">http://www.mrc-lmb.cam.ac.uk.

The MRC Laboratory of Molecular Biology is a research institute within UK Research and Innovation (UKRI).  UKRI is an entity that brings together nine partners to create an independent organisation with a strong voice for research and innovation, more information can be found at www.ukri.org .

">http://www.ukri.org">www.ukri.org.

Working for UKRI MRC provides a whole host of benefits including a defined benefit pension scheme, excellent holiday entitlement (40 ½ days including bank holidays and privilege days) and Benenden Healthcare membership.  You will also have access to employee shopping / travel discounts, on site sport and social facilities, as well as salary sacrifice cycle to work schemes and childcare vouchers.

To apply and access full details of the vacancy please visit our job board at https://mrc.tal.net/vx/appcentre-int/candidate/post/3047/en-GB .

">https://mrc.tal.net/vx/appcentre-int/candidate/post/3047/en-GB">

...

If you are unable to apply online please contact us at recruit">mailto:recruit@mrc-lmb.cam.ac.uk">recruit @mrc-lmb.cam.ac.uk.

Closing date: 20 Dec 2020

Final appointments will be subject to a pre-employment screening.

The Medical Research Council is an Equal Opportunities Employer who participates in the Disability Confident scheme.



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