Cancer Computer Scientist

Job id: 087086. Salary: £43,205 per annum, including London Weighting Allowance.

Posted: 28 March 2024. Closing date: 25 April 2024.

Business unit: Faculty of Life Sciences & Medicine. Department: Comprehensive Cancer Centre.

Contact details:Anita Grigoriadis. [email protected]

Location: Guy's Campus. Category: Research.

Seeking a highly motivated Research Associate with expertise in deep learning and spatial biology within the field of translational cancer research. The project will entail algorithm development and deployment of deep learning approaches for histomorphological characterisation of triple negative breast cancers. Through spatial transcriptomics, diverse transcriptional profiles will be mapped to regions of interest to decipher immune cell population dynamics in triple negative breast cancers. Subclonal and clonal T cell dynamics in these samples can be further investigated using TCR-sequencing.  

This applicant will join the multidisciplinary Cancer Bioinformatics group (http://cancerbioinformatics.co.uk/ ) within the Breast Cancer Now Research Unit at King’s College London whose collective aims are to implement computational approaches for the integrated multi-modal analyses from model systems and patient studies of triple-negative breast cancers. We lead on the latest technologies to perform subcellular spatial transcriptomics and hold a wealth of whole slide image data for digital pathology approaches.

Applicants should have a strong computational background and expertise in dealing with large datasets. Excellent programming, data analysis, statistics and deep learning skills are required. Experience with diverse molecular data is desirable. Applicants will hold a postgraduate degree or equivalent experience in a relevant role. The ideal candidate should be passionate about translating analytical approaches into clinical practice and highly motivated to work in a fast-paced and highly collaborative environment.

The post will be based in Dr Grigoriadis’ Cancer Bioinformatics Team at Guy’s Cancer Centre at Guy’s Hospital and will be expected to interface with colleagues, clinical investigators, and other research fellows during design, development and testing of algorithm.  

This post will be offered as a fixed-term contract for 12 months.

The is a full-time post - 100% full time equivalent.