Bioinformatician

We are seeking a highly motivated and enthusiastic Bioinformatician to join the Teichmann lab within the Wellcome Sanger Institute.

You will work within a Translational science team and perform analysis as well as participate in building computational models at the intersection of fast-evolving areas of single cell genomics, therapeutic target discovery and in vitro cell type derivation. The current intention is that, over the next 12 months, insights and methods currently being developed in the Teichmann group will be used to establish a stand-alone company and there would be an opportunity to transfer the post-holder employment from Genome Research Limited to the newly founded company.

About Us:

The Teichmann lab uses cutting edge single cell genomics technologies and computational methods to understand genes, proteins and cells in human health and disease. We have a long-standing interest in understanding global principles of gene regulation, protein interactions and have a particular interest in immunity. We are focused on using single-cell approaches, cell atlas technologies, and understanding human genetics at the cellular level. The team combines cutting-edge techniques in wet and dry labs and applies these methodologies for further understanding of human health, development and disease.

The Role:

Key responsibilities:

• You will be responsible for developing and maintaining an automated pipeline to handle large scale single cell multiome data analysis for target identification.
• Perform bioinformatics analysis and computational model development for opportunities with translational potential
• Contribute to development of machine-learning approaches to aid target identification, prioritisation, and cell type engineering in vitro.
• Work in collaboration with the Teichmann group to develop innovative data mining strategies in order to answer translational science questions, ensuring throughput and quality.

 About you:

This role would suit somebody with experience in handling genomic data and curiosity to pursue translational science questions based on large single cell data. You will curate, manage and perform high quality data analysis of genomics data to answer specific translational science questions related to in vitro cell type derivation and target identification and provide feedback to other translational and wet lab scientists. In addition to strong communication skills, you will be highly organised with a diligent approach to information gathering.

Please apply with your CV and a Cover Letter outlining how you meet the criteria set out above and in the job description.

Applications will be considered on an ongoing basis and the role may close early when a successful appointment has been made.