Job id: 086806. Salary: £43,205 - £45,521 per annum, including London Weighting Allowance.
Posted: 22 March 2024. Closing date: 15 April 2024.
Business unit: Faculty of Life Sciences & Medicine. Department: Medical & Molecular Genetics.
Contact details:Matthew Brown. [email protected]
Location: Guy's Campus. Category: Professional & Support Services.
Job description
Summary of the Job: Unlocking Genetic Mysteries in Bone and Joint Diseases
As a Bioinformatician in the Department of Medical and Molecular Genetics, you will play a pivotal role in advancing our understanding of common and rare bone and joint diseases, with a particular focus on ankylosing spondylitis. Joining the esteemed research group led by Professors Matt Brown and Emma Duncan, you will contribute to groundbreaking genetic analyses that aim to unravel the intricate complexities of these debilitating conditions.
Purpose of the Role
The primary purpose of this role is to harness advanced bioinformatics approaches to decode the genetic underpinnings of bone and joint diseases including identification of new disease-associated loci and downstream analyses. This will include investigating functional mechanisms of disease, research into polygenic risk scores (including clinical implementation) and identification of novel therapeutic interventions and personalized treatment strategies.
Responsibilities
As a key member of our research team, you will collaborate closely with Professors Matt Brown and Emma Duncan, contributing to gene-mapping studies, functional genomics analysis and polygenic risk score studies. Your expertise will be instrumental in fostering collaboration within our global network of researchers, collectively working towards advancing our understanding of bone and joint diseases. Additionally, you will be responsible for translating complex genetic data into meaningful insights, fostering a collaborative and innovative research environment.
About the Department and University
The Department of Medical and Molecular Genetics at King's College London is at the forefront of human genetics research, boasting a rich history of groundbreaking discoveries. As a leading global university, King's College London provides an intellectually stimulating environment, nurturing creativity and innovation. Researchers in the department have access to state-of-the-art facilities and resources, facilitating cutting-edge genetic research.
Join us in a department known for its commitment to excellence and innovation, where your contributions will shape the future landscape of genetic research. This position offers a unique opportunity to work within a renowned institution, contributing to the global advancement of knowledge in medical and molecular genetics.
If you are passionate about making a significant impact in the realm of genetic analysis and eager to contribute to transformative research, we invite you to be part of our dynamic team at King's College London.
This post will be offered on an a fixed-term contract for 12 months.
This is a full-time post.
Key responsibilities
- Utilise sophisticated bioinformatics techniques to conduct comprehensive genetic analyses of common and rare bone and joint diseases, with a particular emphasis on ankylosing spondylitis
- Actively participate in gene-mapping studies, functional genomics analysis, and polygenic risk score studies. Foster collaboration within the research team and the global network of collaborators
- Play a pivotal role in translating complex genetic data into meaningful insights, contributing to the understanding of the genetic basis of bone and joint diseases. Facilitate the application of genetic findings in the development of targeted therapies and personalised treatment strategies
- Engage with collaborators from around the world, contributing your expertise to collaborative efforts that advance genetic research. Actively participate in the exchange of knowledge and data within the global research community
- Stay abreast of the latest developments in bioinformatics, genetics and related fields. Contribute to the ongoing innovation within the Department of Medical and Molecular Genetics at King's College London, driving the research agenda forward
The above list of responsibilities may not be exhaustive, and the post holder will be required to undertake such tasks and responsibilities as may reasonably be expected within the scope and grading of the post.
Skills, knowledge, and experience
Essential criteria
Desirable criteria
We ask all candidates to submit a copy of their CV and a supporting statement, detailing how they meet the essential criteria listed in the advert. If we receive a strong field of candidates, we may use the desirable criteria to choose our final shortlist, so please include your evidence against these where possible.
This post is subject to Occupational Health clearance.
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