Advanced Research Assistants- Cellular Genetics

An exciting opportunity has arisen for Advanced Research Assistants to support the research of the Cellular Genetics Programme, as a member of the core wet lab support team. You will join a dynamic team and work collaboratively across the Programme, the Sanger Institute and the wider scientific community to support a variety of projects contributing towards the Human Cell Atlas work being undertaken in Cellular Genetics.

You will play a fundamental role within the team which provides expertise to support; the development and implementation of pioneering spatial genomic technologies and also bespoke sequencing library creation for gene expression, immune cell profiling and chromatin accessibility analysis of single cells or nuclei in preparation for downstream NGS analysis.

You will carry out a variety of laboratory protocols and procedures including but not limited to: RNA/DNA extraction, RNA/DNA NGS library preparation and tissue dissociation protocols in preparation for single cell or nuclei RNA sequencing. You will work to test and implement new protocols and scale them up as required by the faculty research groups, working towards delivering the protocols without requiring close supervision. Occasional out-of-hours work may be required of this role.

Excellent communication and relationship-building skills alongside strong time management and organisational skills are needed as is the ability to troubleshoot and identify areas for process improvement.

This is an excellent opportunity for a motivated and adaptable individual to support the cutting edge science delivered within the Cellular Genetics Programme.

Essential Skills
Technical Skills:

Degree in Biological Sciences, or equivalent qualification
Relevant, post-graduate laboratory experience
Significant experience of core molecular biology techniques, including PCR, RNA/DNA extraction, library preparation and similar
Ability to learn new protocols and then run them independently
Ability to test and implement new approaches and techniques
Proven process improvement/troubleshooting ability
Computer literate
Excellent laboratory practice
Competencies and Behaviours

Good written and oral communication skills
Excellent organisational skills
Ability to keep good up-to-date records with attention to detail
Ability to work to a schedule and successfully manage and prioritise multiple competing projects
Proven experience of working within a team
Experience of working on collaborative projects
Other information
Application Process:

Please apply with your CV and a Cover Letter outlining your suitability for the role addressing the criteria set out above.

Contract types:

We have a permanent and fixed term contracts available, this can be discussed further with you at interview stage.