Research Assistant - Molecular Biology

Updated: 2 months ago
Job Type: FullTime
Deadline: 12 Apr 2020

The Genome Engineering and Measurement Lab (GEML) develops, implements, optimises, and analyses cutting edge genome engineering tools and techniques supporting a wide range of research projects at ETHZ, UZH and the USZ.
We are seeking a Research Assistant (Molecular Biology) to support our operations in preparing and validating resources and reagents for downstream genome engineering workflows. The successful applicant will be responsible for the generation of CRISPR/Cas vectors and libraries, the generation and purification of Cas protein variants, and the validation of reagents through cellular and molecular assays. The research assistant will work together with a group of other technicians, graduate students, and senior scientists to streamline and optimise experimental procedures.

We are part of ETH Zuurich and the Functional Genomics Center of Zurich (FGCZ) and are located in the Institute of Molecular Health Sciences at the ETH Hönggerberg campus. The laboratory works in a fast-moving field, ensuring a thrilling environment. The Research Assistant position is initially for 6 months and extendable based on the success of the projects and evaluation of performance for up to a maximum of three years.

Job description
  • Molecular biology, such as cloning, PCR, qPCR
  • Lentiviral packaging and validation of CRISPR/Cas vectors
  • Protein expression and purification (E.coli)
  • Assisting in the organization and maintenance of the core molecular biology reagents

Your profile

The ideal candidate will be very well organised and able to work efficiently and with precision in a fast paced environment. You are proactive and can work independently but also as a part of a small group. You can use technology to manage and share information. Advanced knowledge of English is essential, as it is the working language of the lab.

Required skills:

  • Molecular Biology qualification (e.g. B.Sc. degree or equivalent)
  • Experience with basic molecular biology (e.g. cloning and PCR)

Preferred skills:

  • Experience with CRISPR/Cas genome engineering

Desired skills:

  • Experience with protein purification
  • Mammalian cell culture experience

ETH Zurich

ETH Zurich is one of the world’s leading universities specialising in science and technology. We are renowned for our excellent education, cutting-edge fundamental research and direct transfer of new knowledge into society. Over 30,000 people from more than 120 countries find our university to be a place that promotes independent thinking and an environment that inspires excellence. Located in the heart of Europe, yet forging connections all over the world, we work together to develop solutions for the global challenges of today and tomorrow.


We look forward to receiving your online application with the following documents:

  • Letter of motivation (stating a tentative starting date)
  • CV
  • Diplomas and/or certificates of employment
  • Contact details of two referees

While there is no deadline for applications, we suggest applying by the end of April to ensure full consideration. We are constantly reviewing incoming applications until a suitable candidate has been identified.

Please note that we exclusively accept applications submitted through our online application portal. Applications via email or postal services will not be considered.

Questions regarding the position should be directed to Dr. Zacharias Kontarakis (no applications).

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