Postdoctoral positions: data integration of -omics data for personalized health

Our groups are tightly embedded in the Swiss initiatives on personalized health promoted by the PHRT and SPHN networks. Our major task is to contribute an in-depth molecular analysis of samples from patients to support therapeutic decisions and the discovery of novel targets. These activities are carried under the umbrella of the Swiss Multi-Omics Center (SMOC ), which also unites the expert on clinical genomics of the Health2030 Genome Centre in Geneva. A recently published study of the molecular basis of methylmalonic aciduria in infants provides a representative example of the studies we perform.

With the great progress made in recent years in the digitization of clinical samples by mass spectrometry, the challenge shifted from data generation to data interpretation. More efforts are needed to translate data into information and insights that are actionable. To work on these challenges, we are seeking two candidates that will pioneer reusable workflows for the analysis, integration, and visualization of molecular data. You are expected to build on domain knowledge and create pipelines that simplify data interrogation by non-experts or clinicians. As a member of our team, you will be working in a highly collaborative environment and be involved in national and international networks for precision medicine. You will be expected to work side-by-side with wet-bench scientists and assist in delivering data analyses that fill the gap between data and information and support clinical decisions with deep molecular evidence.

Job description

You are expected to:

• Design and implement reusable analysis and visualization workflows for large scale clinical omics data, with a focus on proteomics and/or metabolomics data.
• Collaborate with the members of the SMOC in Zurich and Geneva on the analysis of multi-omics data, and with specialists of the Swiss Data Science Center .
• Interface with clinicians at the data analysis stage.

Your profile

Essential qualifications:

• PhD in biological sciences with a strong focus on proteomics or metabolomics data analysis.
• Must be well versed with various programming languages, and have a passion for the design and implementation of effective UI.
• Proficiency in written and verbal English communication.
• Positive attitude toward collaborative work and learning of novel technologies.
• Experience in any of the following fields is also highly desirable: multi-omics data integration, containerization technologies, Unix/Linux, data driven analysis, statistics, machine learning, data visualization. 

We offer

ETH Zurich is a family-friendly employer with excellent working conditions. You can look forward to an exciting working environment, cultural diversity and attractive offers and benefits.

Working, teaching and research at ETH Zurich
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Curious? So are we.

We look forward to receiving your online application with the following documents:

• CV
• A motivation letter stating own visions and specifying any past experience that is aligned with the job profile.
• Name and contacts of two referees

Please note that we exclusively accept applications submitted through our online application portal. Applications via email or postal services will not be considered.

Questions regarding the position should be directed to Dr Nicola Zamboni, email nzamboni@ethz.ch (no applications).

About ETH Zürich

ETH Zurich is one of the world’s leading universities specialising in science and technology. We are renowned for our excellent education, cutting-edge fundamental research and direct transfer of new knowledge into society. Over 30,000 people from more than 120 countries find our university to be a place that promotes independent thinking and an environment that inspires excellence. Located in the heart of Europe, yet forging connections all over the world, we work together to develop solutions for the global challenges of today and tomorrow.