Postdoc Position in New Single-Molecule Proteomics Methods
The Laboratory of Chemical and Biological Probes (Prof. Rivera-Fuentes) is looking for a postdoctoral researcher to work on the development of a new method for single-molecule protein identification. We recently demonstrated a new method (called “blinkognition”) to identify peptides with single-molecule resolution. You can learn about this method by reading our recent paper and also by watching this simple explainer video . The goal of the project is to extend this technique to full-length, folded proteins.
As a postdoc working on this project, you would express and purify proteins, label them using a variety of bioconjugation strategies, immobilize them onto a glass surface, perform single-molecule fluorescence measurements using a TIRF microscope, and analyze their traces using our recently developed deep-learning model. You would also develop new analysis pipelines in collaboration with a machine learning specialist in our lab. Additionally, you would be an active member of our lab, contributing to routine lab maintenance, participating in group meetings and in selected teaching/outreach activities. You would also write reports and papers, and prepare presentations for national and international conferences.
Highly motivated scientist with a solid background in chemistry, biochemistry, or biophysics. Strongly interested in developing new technologies to analyze proteins with single-molecule resolution and revolutionize the field of proteomics. Previous experience in protein chemistry, single-molecule imaging, and/or machine learning is an advantage. PhD degree in chemical/physical/biological science and proficiency in oral and written English are formal requirements.
What we offer
We are a dynamic, interdisciplinary, medium-size lab working at the interface of chemistry and biology. We work on the development of probes to visualize and control biological processes in living systems. World-class infrastructure is available in our lab, the department, or at technology platforms of the University of Zurich. We are located at University of Zurich, Irchel campus, where you would work in one of the newest and most modern chemistry buildings in Europe.
Place of work
University of Zurich Irchel, Winterthurerstrasse 190, 8057 Zürich, Switzerland
Start of employment
Employment start date to be mutually agreed.
Please submit your application as a single PDF file including a motivation letter, CV and a copy of your most important publication, along with a short statement of its significant. Letters of recommendation will only be required for shortlisted candidates. Applications will be received until February 25, 2023. Incomplete applications or those arriving after the deadline will not be considered.
UZH on social media
Opportunities For A Postdoc In Quantitative Biochemistry To Probe The Dynamics Of Eukaryotic Dna Replication, Delft University of Technology, Netherlands, about 21 hours ago
Job description We are looking to an ourstanding experimentalist for this exciting NWO-funded project at the interface of biochemistry and biophysics that has as its goals to understand the dynami...
Ph D Or Postdoc On Single Molecule Biosensing Using Plasmon Enhanced Fluorescence, Eindhoven University of Technology, Netherlands, about 5 hours ago
Position PhD-student, (Post-doctoral) Researcher Irène Curie Fellowship No Department(s) Applied Physics and Science Education Reference number V34.6256 Job description The Molecular Plasmonics gr...
Postdoc Position In The Field Of Organic Chemistry And Artificial Enzyme , University of Southern Denmark, Denmark, about 2 hours ago
The Department of Physics, Chemistry and Pharmacy , SDU in Odense invites applications for a postdoc position in the field of organic chemistry and artificial enzyme in the Dr Changzhu Wu group . ...
Postdoc Position In The Field Of Supramolecular Chemistry And Polymer Catalysis , University of Southern Denmark, Denmark, about 2 hours ago
The Department of Physics, Chemistry and Pharmacy , SDU in Odense invites applications for a postdoc position in the field of Supramolecular Chemistry and Polymer Catalysis in the Dr Changzhu Wu g...
Opportunities For A Postdoc In Biophysics To Probe The Dynamics Of Eukaryotic Dna Replication, Delft University of Technology, Netherlands, about 21 hours ago
We are looking to an ourstanding experimentalist for this exciting NWO-funded project at the interface of biophysics and biochemistry that has as its goals to understand the dynamics of eukaryotic...
Opportunities For A Postdoc In Quantitative Biochemistry To Probe The Dynamics Of Eukaryotic Dna Replication, Delft University of Technology (TU Delft), Netherlands, 6 days ago
Opportunities for a postdoc in quantitative biochemistry to probe the dynamics of eukaryotic DNA replication Opportunities for a postdoc in quantitative biochemistry to probe the dynamics of eukar...