Lab technician in Precision medicine at University of Zurich and ETH Zurich
The Department for Quantitative Biomedicine performs research and teaches at the interface of biomedicine, biotechnology and computational biology. The aim is to develop the basis for new approaches in the field of precision medicine. Research and teaching take place in a highly dynamic and internationally embedded environment.
Cancer is a complex tissue disease that involves multiple cell types including tumor, immune and stromal cells. These cells influence each other to dictate the outcome of the disease. Characterizing the cellular components and understanding the workings of the tumor ecosystem is critical to identify the most appropriate treatment for each individual patient.
Bodenmiller Lab is among the pioneers in the development and application of single-cell approaches for the comprehensive analysis of tumor ecosystems. Our mass cytometry based approaches enable simultaneous analysis of over 40 protein and transcripts in single cells in suspension and in tissues.
We are looking for a highly motivated research technician to join the lab and provide technical support in tissue sample preparation, antibody validation, tissue section/single cell staining and data acquisition based on mass cytometry and imaging mass cytometry approaches.
This work will be embedded in two clinical projects, one driven by the European IMMUcan consortium and one driven by the Swiss Personalized Health Network (SPHN). Here basic researchers, clinicians and data analysists from industry and academia have the goal to characterize the tumor microenvironment a high number of patients to ultimately understand the best treatment options. The lab technician will be located at the Irchel Campus of the University of Zurich.
In this position you will:
- work in a collaborative and interdisciplinary team at the interface between the clinic, academia and industry
- antibody labelling, testing and validation
- prepare tissue samples for immuno-fluorescence and imaging mass cytometry
- quality control immuno-fluorescence images
- generate imaging mass cytometry data and perform basic data analysis
- Establish and optimize novel protocols
- a highly motivated lab technician with expertise in tissue handling and demonstrated ability to work in a highly organized and reliable way, with a passion for science who would like to work in a collaborative multidisciplinary research environment that combines systems biology, tumor biology, bioinformatics, and biomedicine.
- an education as a laboratory technician or masters degree
- excellent skills in handling clinical samples
- technical experience tissue handling and imaging
- optionally: experience in single-cell analysis
- a desire to work in a collaborative environment
- a good proficiency in English (German is optional)
What we offer
We offer an attractive package in a dynamic and interdisciplinary work environment, which offers many opportunities for the applicants professional development. The salary is calculated according to cantonal regulations.
For additional information about an employment at the University of Zurich please visit "Working at UZH"
Send by email a cover letter (including an explanation of your motivation), your CV, and the contact information of at least two references to Prof. B. Bodenmiller. Applications will be considered until the position is filled.
Place of work
Winterthurerstrasse 190, Zürich, Switzerland
Start of employment
Employment start date January 2023 or to be mutually agreed. Please submit your application by 30.11.2022.
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