University of Zurich's Center of Dental Medicine is one of the four dental university centers of Switzerland. It has approximately 390 employees and comprises six clinics, an institute, and a central administration department.
Hydrogels are known by their excellent biocompatibility, causing minimal inflammatory response and tissue damage. Photo-polymerizable, injectable hydrogels have been utilized as a minimally invasive option compared to metal coils for the treatment of brain aneurysms, which is a life-threatening cerebral haemorrhage, often resulting in death or severe brain damage. An improved version of this class of hydrogels used in neurosurgery will be further developed as dental biomaterial. Root-canal treatments are among the most difficult clinical applications in dentistry. Unsuccessful treatments yield to failure of the treatment or reinfection of the tooth. Given the fact that unsuccessful root canal treated teeth have less favorable prognosis especially under reconstructions, in part also due to the complex anatomy of the root canals, the group of Prof. Mutlu Özcan is developing a new root canal treatment solution in collaboration with Dr. M. Bispinghoff, Dr. A. Schmocker from the Medtech startup Lumendo and Swiss Federal Institute of Technology (ETH Zurich). This innovative, low-viscosity, injectable material will be implemented as a photo-activated root canal sealer in dentistry. This innovation will allow for a minimally invasive, easy-to-use root canal filling material, which will have the potential to make the treatment faster and easier and thereby improve the treatment outcome and help people keep their natural teeth longer.
The multidisciplinary project, combining material science and bioengineering technologies, is funded by Innosuisse Grant of the Swiss Innovation Agency (2020-2022) grant for the project "Photo-polymerizable Root Canal Filling Material Development".
- Plan, carry out and document development and testing activities to ensure efficacy and safety of the material to be developed.
- Plan and carry out preclinical studies to prove the long-term material performance.
- Carry out risk assessments, set and document material specifications.
- Develop a suitable illumination device for photo-polymerization of the material.
- Pursuing relevant test methods in the field of polymerization.
- Should be a holder of Master's degree in biomedical engineering or similar.
- Should have at least 1 year of relevant industry experience in medical device development.
- Should have experience with the development and testing of dental biomaterials.
- Should have experience in diverse biomaterials research.
- Should have deep scientific understanding, problem-solving skills, and master creative, critical thinking.
- Should be highly motivated, responsible, independent and have well-organized working style.
- Should master English in speaking and writing.
- Should have skills in presentation and operation using both Microsoft Office and Mac.
What we offer
- Highly innovative research project aiming to develop a dental biomaterial that can help improve people's health.
- An interdisciplinary working environment, giving high responsibility and freedom.
- Working with young, entrepreneurial and motivated team.
- Attractive 9-months 100% employment contract (expected date of project end: 31 December 2021).
Place of work
Center of Dental Medicine
Start of employment
As soon as possible.
An application requires a written solicitation, extended CV, and two references with contact information. The selection will be based on the comparison of the submitted applications, including an interview with the pre-selected candidates.
Applications to be sent to Prof. Dr. Dr. h.c., Mutlu Özcan, PhD before 24 March 2021:
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