Senior Research Engineer at Chalmers Mass Spectrometry Infrastructure

9 Feb 2024
Job Information

Organisation/Company

Chalmers University of Technology

Research Field

Chemistry » Biochemistry

Researcher Profile

First Stage Researcher (R1)

Country

Sweden

Application Deadline

14 Mar 2024 - 22:00 (UTC)

Type of Contract

Temporary

Job Status

Full-time

Is the job funded through the EU Research Framework Programme?

Not funded by an EU programme

Reference Number

304--1-12589

Is the Job related to staff position within a Research Infrastructure?

No

Offer Description

SciLifeLab is a national research infrastructure that fosters collaboration among researchers from different areas of life sciences. Its mission is to advance life sciences for the benefit of society by providing cutting-edge technologies and deep scientific expertise. At SciLifeLab, we provide access to a range of pioneering technologies in molecular biosciences. The research infrastructure enable scientific endeavours of users from academia, industry and health care. Dedicated staff scientists can offer support throughout the experimental process – from study design to data handling.

About the position

The SciLifeLab Metabolomics Platform is seeking a highly motivated Senior Research Engineer with extensive experience from Metabolomics to join our team at the Chalmers Mass Spectrometry Infrastructure (CMSI), Gothenburg, Sweden. The Platform services include both targeted and untargeted metabolomics profiling as well as absolute quantification of small molecules. The successful candidate will be a key resource at CMSI, providing general expertise in small molecule mass spectrometry and metabolomics in particular, including in-depth knowledge of tools and analysis strategies. Tasks will include providing hands-on support and guidance in metabolomics from wet-lab to data-processing and -analysis. Furthermore, to provide general support to platform users and the surrounding research environment trough expert competence in the field. The candidate is expected to have high ability to work both independently and as part of the facility team.

Major responsibilities

70% - Metabolomics and other small molecule mass spectrometry projects, including method development, sample preparation, data generation, data processing and analysis, reporting and support to the project owner.

• Participate in design and take ownership for the execution of metabolomics experiments in support projects.
• Operate metabolomics workflows, including sample preparation, method development and validation, data acquisition, processing and analysis, and reporting.
• Troubleshoot, optimize, and implement assays on a range of mass spectrometers.

15% - Instrument maintenance and troubleshooting, general laboratory maintenance, writing and updating standard operating procedures, invoicing, ordering, receiving of goods and other general tasks.

• Maintenance and troubleshooting of chromatography and mass spectrometry systems including UHPLC, GC, qTOF, IM-qTOF, MS/MS and other systems.
• Maintain updated knowledge on state-of-the-art applications and technologies to ensure that the platform remains at the forefront in metabolomics.
• Implement and help platform users to implement targeted analysis methods.
• Write and update standard operating procedures.
• Maintain other relevant documentation, such as for example invoicing and requisitioning documents.
• Monitor and maintain laboratory appearance.

15% - Support and train platform users and other personnel in metabolomics and other relevant techniques

• Support and train platform users and other personnel in metabolomics and other relevant techniques and analysis.
• Provide expert advice on technical questions related to metabolomics and small molecule analysis.
• Participate in relevant meetings.

Qualifications

• A PhD in a relevant field or an MSc with a minimum of four additional years of experience in working with metabolomics and small molecule mass spectrometry applications.
• Demonstrated experience in untargeted and targeted metabolomics experiments, LC-MS method development, method validation and troubleshooting.
• Experienced user of UHPLC-HRMS (qTOF, Orbitrap) and UHPLC-MS/MS systems.
• Proficiency in tools used in metabolomics data processing and analysis, preferably in R or Python environment.
• Experience that demonstrates the ability to follow relevant state-of-the-art techniques in the field.
• Demonstrated experience in good communication and collaboration skills with the ability to work effectively in a multi-cultural team-oriented environment.
• Strong organizational and interpersonal skill and willingness to work with sample analysis.

Preferred Qualifications

• PhD in biochemistry, analytical chemistry, or related field with a focus on metabolomics.
• Expert user of UHPLC-HRMS and UHPLC-MS/MS systems.
• Experience in maintenance of GC and LC systems.
• Experience with metabolomics data processing and analysis solutions in R or Python or in other open-source solutions.
• Ability to drive scientific support projects together with a continuous development mindset.
• Experience in project management and working in scientific environments supported by strong oral and written skills in English. Oral and written skills in Swedish are seen as an asset.

Contract terms
This position is a full-time permanent employment.

For more information about what we offer and the application procedure, please visit Chalmers website. 

*** Chalmers declines to consider all offers of further announcement publishing or other types of support for the recruiting process in connection with this position. *** 

Chalmers University of Technology conducts research and education in engineering sciences, architecture, technology-related mathematical sciences, natural and nautical sciences, working in close collaboration with industry and society. The strategy for scientific excellence focuses on our six Areas of Advance; Energy, Health Engineering, Information and Communication Technology, Materials Science, Production and Transport. The aim is to make an active contribution to a sustainable future using the basic sciences as a foundation and innovation and entrepreneurship as the central driving forces. Chalmers has around 11,000 students and 3,000 employees. New knowledge and improved technology have characterised Chalmers since its foundation in 1829, completely in accordance with the will of William Chalmers and his motto: Avancez!

 

Requirements

Research Field

Chemistry

Education Level

PhD or equivalent

Languages

ENGLISH

Level

Excellent

Research Field

Chemistry » Analytical chemistry

Years of Research Experience

4 - 10

Additional Information
Work Location(s)

Number of offers available

1

Company/Institute

Chalmers University of Technology

Country

Sweden

City

Göteborg

Postal Code

41296

Street

Chalmers Tekniska Högskola

Where to apply

Website

https://www.chalmers.se/en/about-chalmers/work-with-us/vacancies/?rmpage=job&rm…

Contact

City

Göteborg

Street

Chalmers Tekniska Högskola

Postal Code

41296

STATUS: EXPIRED