Researcher in Pharmacokinetic-Pharmacodynamic modelling

Published: 2022-08-16

Uppsala University is a comprehensive research-intensive university with a strong international standing. Our ultimate goal is to conduct education and research of the highest quality and relevance to make a long-term difference in society. Our most important assets are all the individuals whose curiosity and dedication make Uppsala University one of Sweden’s most exciting workplaces. Uppsala University has over 54,000 students, more than 7,500 employees and a turnover of around SEK 8 billion.

The Department of Pharmacy at Uppsala University has an interdisciplinary environment at the center of the pharmaceutical arena. With frontline research, first-rate education and extensive collaborations we constitute an important driving force in the development of our academic field. In this inspiring environment our rich diversity of research groups, several of international prominence, develop and conduct work of great scientific importance. Among our core competences are pharmacokinetics-pharmacodynamics, computational modelling and simulations, in vitro ADME models, advanced in vivo methods, as well as patient and societal aspects, from optimizing the use of drugs in individuals to societal pharmaceutical policies. Together, we form a unique cluster of academic competences within pharmaceutical science, playing a key role in shaping the future of pharmacy in both Sweden and globally.

Our scientific focus areas in selection: Pharmacodynamics • Pharmacokinetics • Pharmacometrics • Biologics • Clinical Pharmacy • Drug Delivery • Molecular Pharmaceutics • Pharmaceutics and Nanotechnology • Pharmacoeconomics • Pharmacoepidemiology • Pharmacotherapy • Social Pharmacy

 More information www.farmaci.uu.se

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Duties/Project
The project will involve establishment of pharmacokinetic (PK) and pharmacodynamic (PD) relationships based on preclinical and clinical data for new and available antibiotics and nanoparticles. Pharmacometric models will be developed based on in vitro, in vivo and literature data. The models aim to bridge (translate) exposure-response relationships from animals to humans in order to optimize clinical dosing. The project is part of a new research environment and involves collaboration with expertise in nanoparticle technology, microbiology, infectious diseases and organic chemistry. We expect that the project will lead to new advances in predictive and quantitative methods for characterizing pharmacokinetics and pharmacodynamics in the field.

Requirements/Qualifications
Eligible to be employed as a researcher is a person who has completed a doctoral degree (PhD) in pharmacokinetics / pharmacodynamics / pharmacometrics or a related field or has a foreign degree that is deemed to correspond to a doctoral degree in the specified field.

We place great emphasis on personal suitability and motivation to improve methods for antibiotic development and antibiotic use. The applicant must be able to express themselves well, both orally and in writing, in English.

Additional qualifications
Pharmacokinetic-pharmacodynamic modeling and simulation of antibiotics and/or nanoparticles. Experience of model-based translation from preclinic to clinic for antibiotics in drug development. Interest in, and skill in, scientific writing is highly desirable, as is experience of collaborating in international networks.

Application
The application should include (i) a motivation letter with a brief description of the candidate and research interests as well as experiences in relation to the requirements and qualifications listed above, and the topics pharmacometrics, pharmacokinetics, pharmacodynamics and oncology (ii) the candidate's CV, (iii) copies of diplomas and certificates, (iv) two recommendation letters (where one preferably would be from a supervisor of the Master thesis) and (v) thesis, as well as other relevant documents that the applicant wish to refer to, such as proficiency in English.

About the employment
The employment is a temporary position, 12 months. Scope of employment 100%. Starting date 15 October or as agreed. Placement: Uppsala

For further information about the position, please contact: Professor Lena Friberg, [email protected] .

For questions around the employment, please contact personnel coordinator Pernilla Larsson [email protected] .

Please submit your application by 9 September 2022, UFV-PA 2022/2934.

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Submit your application through Uppsala University's recruitment system.

Placement: Department of Pharmacy

Type of employment: Full time , Temporary position longer than 6 months

Pay: Individual salary

Number of positions: 1

Working hours: 100%

Town: Uppsala

County: Uppsala län

Country: Sweden

Union representative: Seko Universitetsklubben [email protected]
ST/TCO [email protected]
Saco-rådet [email protected]

Number of reference: UFV-PA 2022/2934

Last application date: 2022-09-09

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