Research Specialist for the division of Biomaterials

The research at the Division for Biomaterials focuses on new bioengineering techniques and new materials for cell biology research. The goal of many of our projects is to develop new methods that will help us and others to better understand biological processes at the nanoscale and up. In particular we are interested in how to control and study cell behaviour through their ability to sense their micro-environment.

We are looking for a Research Specialist to join the research group of Professor Björn Högberg at the Division of Biomaterials. The candidate will lead our super resolution microscopy related projects as well as aid other members of the group and division in their imaging experiments. The successful candidate will also be responsible for the maintenance of our super resolution microscopy instruments as well as train and assist other members of the division in the usage of the instrument.

The focus of the projects are the development of novel, DNA-based labeling methods for high throughput transcriptomics and proteomics using DNA origami or other DNA nanotechnology approaches.

To be eligible for employment as a Research Specialist, in addition to holding a Degree of Doctor, PhD, or having equivalent scientific expertise, the applicant must have demonstrated research expertise as well as have documented research experience after defending their doctoral dissertation.

In order for the applicant to fit in the general theme of the laboratory the applicant should be well experienced in laboratory techniques used for production, purification and characterization of DNA constructs. In addition to this the applicant should have a strong knowledge of software tools and laboratory techniques used  for the production and characterization of DNA origami structures. As the candidate will be responsible for the maintenance and operation of the division’s super-resolution TIRF microscopy instrument the position specifically will require a expert knowledge of the TIRF microscopy technique, the operation and maintenance of TIRF microscopy equipment and localization based super resolution techniques in particular DNA-PAINT, along with related software used for microscope operation and data processing. The work will also include using next generation sequencing techniques, the experience of sample preparation, data generation and processing for such techniques thus is also a strong requirement for the successful candidate. A strong knowledge of programming language (e.g. Python) and software modules used for microscopy and next generation sequencing data processing is also highly encouraged.

After an overall assessment of the expertise and merits of the applicants in relation to the subject area, Karolinska Institutet will determine which of them has the best potential to contribute to a positive development of the activities at KI.

A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world's leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. Karolinska Institutet is a state university, which entitles to several benefits such as extended holiday and generous occupational pension. Employees also have access to our modern gym for free and receive reimbursements for medical care.

Location: Biomedicum, Solna

Högberg Lab

Department of Medical Biochemistry and Biophysics

We prefer that Your application is written in English, but You can also apply in Swedish. An application must contain the following documents: Resumé, qualifications and description of planned research, presented in accordance with Karolinska Institutet's qualifications portfolio.

Welcome to apply at the latest 2nd of September 2021

The application must be submitted through the Varbi recruitment system.