Research Engineer - drug repurposing in viral infections to Karolinska Institutet

We are seeking a highly motivated person to join Päivi Östling team at Department of Oncology-Pathology , SciLifeLab at Solna Campus as a research engineer to work on drug repurposing in viral infections.

Your work will be carried out at the Science for Life Laboratory (SciLifeLab ), which is a leading national infrastructure for next-generation life science research in Sweden. SciLifeLab is jointly operated by the four host universities: Karolinska Institutet, KTH Royal Institute of Technology, Stockholm University and Uppsala University, and it has facilities in four other universities across Sweden. There are over 1000 people working at SciLifeLab, either in research groups or in the infrastructure facilities, most of them in the KI Solna campus and in Uppsala. This position resides at the Solna campus.

Our group does primarily research on precision cancer medicine with the aim of optimizing treatments for individual cancer patients based on molecular profiling and functional drug testing. Additionally, we are developing a novel drug repurposing strategy for SARS-CoV-2 based on host cell responses to drug treatments within the REMEDi4ALL consortium. Our team's overall goal is to develop a drug repurposing framework using screening and omics- profiling to combat viral diseases. www.scilifelab.se/researchers/olli-kallioniemi/

The research engineer will be involved in our ongoing efforts to develop a novel drug repurposing strategy for viral diseases. We work with small-molecule drugs from clinical development or approval and investigate their role and mechanism-of-action in viral infections. We are partners in Horizon EU research consortium REMEDi4ALL which has an overall goal to assemble and operate a drug repurposing platform in Europe. Thereby, your mission is to be part and assist in a leading research environment in Europe for drug repurposing research. The candidate’s focus will be the development, performing and analysis of various cell-based assays by high-content screening, proteomics, transcriptomics, or other methods using various cell lines as infection models.
This work requires creativity, pro-active mindset, and collaborative skills.

We are looking for a talented and highly motivated research engineer interested in drug repurposing, antivirals, virology, and novel biological methods.

Qualifications:

• Qualified candidates have obtained at least a master’s degree in a relevant field, such as biomedical science, molecular and cell biology, or biotechnology.
• Hands-on experience in cell culture techniques is required.
• Applicants with experience in high-throughput screening techniques (Cell-titer Glo- and fluorescence image-based assays), subsequent image analysis and previous knowledge on viral infectious will be prioritized.
• Fluency in English is mandatory

Merits:

• Understanding of data handling and basic bioinformatics skills are highly valued.

The projects are carried out in an interdisciplinary environment that involves collaboration with several groups within Sweden and Europe. Therefore, the candidate should have excellent interpersonal and communication skills, be service-minded and enjoy working in a team.

A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world's leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. Karolinska Institutet is also a state university, which entitles you to several good benefits through our collective agreement. And you get to practice freely in our modern wellness facilities, where trained staff are on site.

Location: SciLifeLab,Solna

Choose to work at KI – Ten reasons why

Welcome to apply at the latest 3th  October.

The application is to be submitted through the Varbi recruitment system.In this recruitment, you will apply with your CV without a personal letter. Instead, you will answer some questions about why you are applying for the job in the application form. 

The position is for 1 year.