Do you want to contribute to top quality medical research?
The Department of Microbiology, Tumor and Cell Biology (MTC) at Karolinska Institutet conducts research and teaching within immunology, infection biology, cell biology and cancer. MTC have about 30 research groups and our key words are multidisciplinary, bridging, national and international collaborations.
The behavior and physiology of microorganisms significantly determines their persistence in the environment and their ability to cause infection. Thereby, biofilm formation of microorganisms is a major cause of environmental persistence, chronic infections and significantly contributes to the emergence and spread of antimicrobial resistance.
Description of the subject area
Ancient microbial biofilm formation is a major cause of environmental survival and chronic infection in all relevant microorganisms. Biofilm formation, the sessile mode of growth, is characterized by the expression of an extracellular matrix composed of amyloid fimbriae and exopolysaccharide and positively regulated by cyclic di-GMP signaling in bacteria. As one subject area, the Ute Römling group has identified the exopolysaccharide cellulose and amyloid curli as the extracellular matrix and (re)discovered cyclic di-GMP in 2004. We are currently studying cyclic di-nucleotide signaling, its regulation and phylogeny in the context of the physiology of the gastrointestinal pathogen Salmonella typhimurium and beyond with innovative experimental approaches.
Your mission
As a research assistant, you will be working primarily with Salmonella typhimurium and Escherichia coli as the model organism. You are, however, expected to flexibly apply similar research questions to other model organisms and to contribute to other ongoing research projects. You are expected to teach experimental approaches to visiting undergraduate and graduate students. You are also expected to collaborate within the research group and externally. Engagement in the preparation of scientific publications is expected. We offer active participation in scientific meetings on all levels.
Working language is English.
Your profile
Requirements for the position:
To be eligible for employment as a research assistant, you must have a Bachelor or Master of Science degree and have demonstrated research expertise and ideally provide documented research experience in the form of publications.
You are the right applicant for this position, if you are self-driven, highly engaged, have ambitious goals, want to do high-quality research and documented achievements.
In addition to the aforementioned requirements, the applicant must have shown:
- Demonstrated experience in molecular (micro)biology techniques in microorganisms
- Demonstrated ability to successfully work on and organize independently research project practically and theoretically
- Demonstrate ability to author and initiate scientific articles
- Demonstrate ability to successfully supervise junior researchers and guide peers in research questions
- Demonstrate ability to work in interdisciplinary teams
- Fluency in written and spoken (scientific) English
- Excellent communication skills
Meritorius for the position:
A plus is if you like to work on the molecular basis of research topics that touch upon challenging and important environmental equally as clinically relevant issues with up to date experimental approaches to create novel knowledge at the forefront of the research fields.
Additional skills that are especially meritorious for the position:
- Theoretical and practical experience to work with either Salmonella typhimurium or Escherichia coli
- Basic knowledge in bioinformatics and/or programming languages
What do we offer?
A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world's leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. Karolinska Institutet is also a state university, which entitles you to several good benefits through our collective agreement. And you get to practice freely in our modern wellness facilities, where trained staff are on site.
Location: Solna
The research group: https://ki.se/en/mtc/ute-romling-group
The department: https://ki.se/en/mtc/department-of-microbiology-tumor-and-cell-biology
Choose to work at KI – Ten reasons why
Application
Welcome to apply at the latest 2024-05-17.
The application is to be submitted through the Varbi recruitment system.In this recruitment, you will apply with your CV without a personal letter. Instead, you will answer some questions about why you are applying for the job in the application form.
Permanent position is initiated by a six months trial period.
Want to make a difference? Join us and contribute to better health for all
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