The lab and technologies
The Jakobsson lab investigates processes of blood vessel morphogenesis/patterning and function in development and disease, with the aim to develop new therapies. The lab utilizes mouse models of human disease based on inducible genetic loss- and gain- of-function in combination with state-of-the-art confocal live imaging (multi-photon, in vivo and ex vivo). In addition, the environment provides access to drug screening platforms, proteomics and single cell RNA sequencing. The lab is integrated in a high-performing interactive scientific environment with close contact with the clinic. Recent publications from the lab: Jin et al, Nat. Cell Biol., 2017 ; Wang et al, Development, 2017 ; Wang et al, Sci. Rep., 2018.
The project, which is funded by the Swedish Brain foundation, aims at identifying and validating new vascular targets to modify angiogenesis and vascular function in genetic disease, stroke and cancer. Data acquisition is facilitated by mouse models in combination with abovementioned technologies, including single cell RNA seq. Please visit the lab website (http://ki.se/en/mbb/lars-jakobsson-group ) for an overview.
The Department and location
The Department of Medical Biochemistry and Biophysics at Karolinska Institutet conducts a broad spectrum of biomedical research and education at the absolute forefront. Presently our department consists of approximately 450 employees. The postdoc will work in Dr. Lars Jakobsson’s group at the Division of Vascular Biology, located in a vibrant environment in a new state-of-the-art research center, Biomedicum, in central Stockholm. Please see Biomedicum Stockholm
We are looking for a highly motivated, creative and interactive team player with a sharp mind and a passion for understanding biology in depth.
To qualify, the applicant must hold (or shortly obtain) a doctor’s degree, acquired maximum two years prior application deadline, in the fields of molecular/ developmental biology, biotechnology/engineering or similar. Previous engagement in developmental biology, vascular biology or neuroscience with experience of confocal microscopy and/or image analysis, in vivo experimentation, tissue culture, cell signalling, cloning and bioinformatics would be an advantage. A strong publication record (at least one first author paper in a recognised international journal) is highly desirable. The candidate should be a self-motivated and driven team worker, with good communication skills. A high level of English, spoken and written, is a requirement.
Type of position
The postdoc position is available immediately. Funding is in the form of a tax-exempt scholarship and ranges between 25 000 to 29 000 SEK/month. This funding is provided for a maximum of two years, with a possibility for extension of another two years on complete salary scheme.
Scholarships for postdoctoral qualification can be established for foreign researchers who place their qualifications in Sweden. The purpose of scholarships for postdoctoral qualification is to promote internationalization and contribute to research qualification after a doctorate or equivalent.
A scholarship for carrying out postdoctoral research can be granted for a maximum of two years within a four year period following the receipt of a doctoral degree or equivalent.
To be eligible for a postdoctoral scholarship, the person must have obtained a doctorate or a foreign degree deemed to be equivalent to a doctorate.
The head of the department determines whether their previous training and scholarly qualifications correspond to a Swedish doctorate or higher.
Type of scholarship
The amount is tax free and it is set for twelve months at a time, paid out on a six months basis. In exceptional cases, shorter periods may be acceptable.
An application must contain the following documents in English or Swedish:
- A complete curriculum vitae, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
- A complete list of publications
- A summary of current work (no more than one page)
The application is to be submitted on the Varbi recruitment system.
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