Postdoctoral researcher in spinal cord regeneration

A postdoctoral position is available in the lab of András Simon at the Department of Cell and Molecular Biology, Karolinska Institute. The lab seeks to reveal mechanisms that are responsible for successful regeneration to occur in salamanders, and conversely, highlight processes that prevent comparable injury responses in mammals.

The Simon lab's primary salamander model is the Iberian newt which has the widest spectrum of regeneration capacity among vertebrates. The lab has established several experimental paradigms both in vivo and in vitro, sequenced the genome of the Iberian newt, established stable transgenesis, and created genome-edited newts. Harnessing these technological developments, the group is combining exhaustive cell tracking studies with massive parallel sequencing and molecular manipulations to gain insights into regulatory mechanisms whose appropriate targeting could impose regenerative traits to mammals.

Research projects in the Simon lab are supported by several funding bodies such as the European Research Commission (ERC), the Knut and Alice Wallenberg Foundation, the Swedish Research Council, the Swedish Cancer Society.

The postdoctoral fellow will work on spinal cord regeneration with special focus on establishment and re-organization of neural networks during regeneration. The work will involve comprehensive mapping of neural networks, cell tracking within the CNS as well as molecular profiling and manipulation of regeneration.

The successful candidate will be part of a highly interactive multinational and multidisciplinary team covering expertise in molecular biology, cell biology, neuroscience, regeneration biology, mathematical modelling and robotics.

The project is supported by an ERC synergy grant. The fundamental questions addressed in the project are outlined in Ryczko, Simon, Ijspeert, 2020, Trends in Neurosciences and references within.

We are seeking an ambitious fellow with a PhD and background in molecular and/or systems neuroscience. Experience with wet-lab single-cell ‘omics protocols and bioinformatics skills are of advantage. Fluency in English, both written and spoken, is a requirement.

Qualified to be employed as a postdoctor is one who has obtained a doctorate or has equivalent scientific competence. Applicants who have not completed a doctorate at the end of the application period may also apply, provided that all requirements for a completed degree are met before the (intended) date of employment. This must be substantiated by the applicant's main supervisor, director or equivalent.

Karolinska Institutet is one of the world's leading medical universities. Our vision is to pursue the development of knowledge about life and to promote better health for all. At Karolinska Institutet, we conduct innovative medical research and provide the largest range of biomedical education in Sweden. Karolinska Institutet is a state university, which entitles employees to several benefits such as extended holiday and a generous occupational pension. Employees also have free access to our modern gym and receive reimbursements for medical care.

Location: Stockholm

An employment application must contain the following documents in English or Swedish:

• A complete resumé, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
• A complete list of publications
• A summary of current work (no more than one page)

Welcome to apply at the latest October 29, 2021.

The application is to be submitted through the Varbi recruitment system.