Postdoctoral researcher in embryonic epigenetics

Within the Lanner laboratory we develop pluripotent stem cell based cellular therapies and explore the mechanisms that control early human embryo development and pluripotency. We have focused on transcriptional characterizations but have recently moved into gene regulation and will now explore epigenetic control of the early embryo. Within this project you will develop and utilize new technologies to perform single cell epigenetic profiling.

You will independently adopt methodologies to perform single cell epigenetic profiling of embryos and stem cell-based embryo models. Functionally you will extend on our recent finding that PRC2 is critical for lineage decision in early human development using genome editing and pharmacological treatments.

You should be highly motivated and interested in developing and performing epigenetic analysis of early human embryos and stem cell models. You should be able to develop single cell-based technologies to profile human embryos and stem cell models. It is important that you are independent, take initiatives and have a very good ability to co-operate. Furthermore, it is important that you are performance-oriented. We value personal qualities in the selection of candidates.

Eligibility requirements

You should be able and have proven track-record of developing epigenetic methodologies and experience in naïve pluripotent stem cells. Good communication skills in English is required.

Qualified to be employed as a postdoctor is one who has obtained a doctorate or has equivalent scientific competence. It is considered as an advantage if you have completed your doctoral degree within the last three years, if there are special reasons, your degree may have been completed earlier. Applicants who have not completed a doctorate at the end of the application period may also apply, provided that all requirements for a completed degree are met before the (intended) date of employment. This must be substantiated by the applicant's main supervisor, director or equivalent.

A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world's leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Karolinska Institutet is also a state university, which entitles you to several benefits through our collective agreement.

Location: Flemingsberg

Choose to work at KI – Ten reasons why

An employment application must contain the following documents in English or Swedish:

A complete resumé, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work A complete list of publications A summary of current work (no more than one page)

Welcome to apply at the latest July 14th 2022.

The application is to be submitted through the Varbi recruitment system.