Postdoctoral Researcher in developmental cardiovascular medicine and stem cell biology

Updated: 5 months ago

Do you want to contribute to top quality medical research?

The Ken Chien group belongs to the Department of Cell and Molecular Biology (CMB) at the Karolinska Institute in Stockholm, one of the world’s leading medical universities. CMB is a department with a strong focus on basic science. CMB conducts research and education in cell biology, molecular biology, developmental biology, stem cell biology, cancer and infection biology. The lab is located in Biomedicum, one of Europe's largest laboratories with ultramodern facilities and rich opportunities for collaboration and career development.

Research group

The central scientific interest of the Chien laboratory is to understand heart development at the molecular and cellular level, with the ultimate goal of applying the developmental principles, logic, pathways, technology, and model systems to unravel human heart disease. We use several different approaches to study heart development, including in vitro stem cell differentiation system and in vivo embryo development studies.


We are seeking a highly motivated and ambitious postdoctoral scientist with a strong background in stem cell and molecular biology. The research project will focus on characterizing the role of tight junctions in mammalian cardiogenesis and tissue repair using mouse models alongside cardiac organoids.

Your profile

It´s required to have a PhD in a relevant area. For success in this position, it is important that the candidate has experience working with mouse models and holds a Function B certificate or equivalent. Additionally, the candidate should have done extensive training in human embryonic stem cell culture, differentiation and manipulation techniques. Experience with advanced microscopy techniques and CRISPR/Cas9 technology for genome engineering is also required. The candidate should thrive in teamwork while being an independent thinker and must speak and write fluent English with excellent communication skills. The candidate’s personal skills will be highly valued.

It´s meriting for the candidate to show experience in the areas of cell adhesions and/or cardiac development/regeneration through publication of high impact research papers. Experience in cell and tissue mechanics, tissue engineering, computational modelling and/or bioinformatic analysis will be considered highly meriting.

To be eligible for employment as a postdoctor a doctoral degree or a foreign degree deemed to be equivalent to a doctoral degree is required. This eligibility requirement must be fulfilled at the latest at the time of the employment decision. It is considered as an advantage if you have completed your doctoral degree within the last three years, if there are special reasons, your degree may have been completed earlier.

What do we offer?

A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world's leading medical universities. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Several of the people you meet in healthcare are educated at KI. A close relationship with the health care providers is important for creating groundbreaking top quality education and research. Karolinska Institutet is also a state university, which entitles you to several benefits through our collective agreement.

Location: Stockholm


We prefer that your application is written in English, but you can also apply in Swedish. An application must contain the following documents:

  • A complete curriculum vitae, including date of the thesis defense, title of the thesis, previous academic positions, academic title, and current position.
  • A complete list of publications with links to degree project and any previous publications
  • A letter of motivation (max. 1 page)
  • A summary of current work (no more than one page)
  • Verification from the thesis defense committee or the equivalent (only if the thesis defense is scheduled within three months after the application deadline)
  • Two letters of recommendation.
  • The application is to be submitted through the Varbi recruitment system.

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