Postdoctoral Researcher in Developmental and Metabolic Biology

Our research interest is to understand the cellular dynamics that drive the formation of different components of the intervertebral discs during embryonic development, and the plasticity of adipose tissue in response to environmental changes (https://ki.se/en/bionut/cellular-and-molecular-mechanisms-underlying-intervertebral-disk-formation-and-diversity-and ). We will mainly use single cell/nucleus RNA sequencing methods combined with genetic lineage tracing to tackle these scientific questions. Our findings will innovate the current research frontier in the fields of developmental and metabolic biology and inspire the develop of novel treatment strategy against spine-related and metabolic disorders.

The postdoc will study the transcriptomic profiles of genetically traced intervertebral disc cells and adipose tissue cells. The research work includes single cell/nucleus data analysis, confocal imaging, immunofluorescence and standard molecular biology techniques. The postdoc is expected to have the ability to independently drive research projects.

We are looking for a highly motivated postdoctoral fellow with strong independent working ability. To address the above-mentioned questions, the candidate must have significant experience in bioinformatic analysis of single cell/nucleus RNA sequencing and spatial sequencing data, demonstrated in the form of published research paper in high-quality internationally peer-reviewed journals. Previous experience in mouse handling, tissue sectioning, immunostaining, confocal microscopy and image processing will be an asset. Fluency in oral and written English, independency in research and good team-working spirit are required.

To be eligible for employment as a postdoctor a doctoral degree or a foreign degree deemed to be equivalent to a doctoral degree is required. This eligibility requirement must be fulfilled at the latest at the time of the employment decision. It is considered as an advantage if you have completed your doctoral degree within the last three years, if there are special reasons, your degree may have been completed earlier.

A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world's leading medical universities. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Several of the people you meet in healthcare are educated at KI. A close relationship with the health care providers is important for creating groundbreaking top quality education and research. Karolinska Institutet is also a state university, which entitles you to several benefits through our collective agreement.

Location: Flemingsberg

https://ki.se/en/bionut/cellular-and-molecular-mechanisms-underlying-intervertebral-disk-formation-and-diversity-and

Choose to work at KI – Ten reasons why

https://ki.se/en/bionut/department-of-biosciences-and-nutrition

An employment application must contain the following documents in English or Swedish:

• A complete resumé, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
• A complete list of publications
• A summary of current work (no more than one page)

The application is to be submitted through the Varbi recruitment system.