Postdoctoral fellow in Single-cell Genomics

Updated: about 2 months ago
Job Type: FullTime
Deadline: 20 May 2022

The Guibentif lab is looking to recruit a post-doctoral fellow. We are a Swedish Research Council-funded group, establishing novel human pluripotent stem cell-based platforms to study human embryonic development and disease. We are affiliated to the University of Gothenburg (GU), one of the largest universities in Northern Europe. Given our affiliation to the Institute of Biomedicine and to the Sahlgrenska Center for Cancer Research, we are part of a supportive interdisciplinary environment, comprising basic developmental biologists as well as clinical scientists.


Research topic

The overall goal of this project is to bridge current in vitro models of human embryonic development with the latest progress in developmental hematopoiesis studied in vivo. This will lead to new frameworks for defining the prenatal transformation events leading to childhood cancer. We harness single-cell genomics, along with a cross-species approach, to chart the mammalian developmental processes modelled during in vitro stem cell differentiation.


Duties 

The selected candidate will be expected to work in a cross-disciplinary team, and to establish single-cell profiling analysis workflows to dissect developmental processes modelled in stem cell differentiation cultures. The selected candidate will carry out aseptic cell culture and molecular biology experiments, and will be expected to take part in manuscript writing and to regularly present his/her own work in group and departmental meetings.


Assessment criteria

Regulations for the evaluation of qualifications for academic positions are given in Chapter 4, Section 3 - 4 of the Higher Education Ordinance.

The candidate selection will be based on the cover letter, Curriculum Vitae, interview and contact with references. See the selection criteria below, in decreasing order of importance:

1 – Expertise in developmental biology, stem cells and/or single-cell profiling techniques

2 – Communication and team work skills

3 – Hands-on experience in chromatin immunoprecipitation, next-generation sequencing library preparation, and/or droplet-based single-cell profiling techniques

4 – Demonstrated skills in human pluripotent stem cell culture and differentiation, fluorescence-activated cell sorting, flow cytometry data analysis, and/or computational analysis of next-generation sequencing data.

Application

Submit your application via the University of Gothenburg’s recruitment portal by clicking the “Apply” button. It is your responsibility to ensure that the application is complete as per the vacancy notice, and that the University receives it by the final application deadline.  

The application should contain:

- A cover letter giving a brief description of previous research experience, and a motivation to why you are applying

- A CV including a list of publications

- Proof of completed PhD

- Contact details of two references


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