Postdoc in Regulatory Genomics at Science for Life Laboratory, KTH

Updated: about 2 hours ago
Deadline: 27 Feb 2020

KTH Royal Institute of Technology in Stockholm has grown to become one of Europe’s leading technical and engineering universities, as well as a key centre of intellectual talent and innovation. We are Sweden’s largest technical research and learning institution and home to students, researchers and faculty from around the world. Our research and education covers a wide area including natural sciences and all branches of engineering, as well as architecture, industrial management, urban planning, history and philosophy.


School of Engineering Sciences in Chemistry, Biotechnology and Health (CBH) is one of the five schools of KTH and a strong constellation for research and education in the broader areas of health, environment, energy and materials.The School of Engineering Sciences in Chemistry, Biotechnology and Health conducts research and education in areas that cover several global challenges. Among them are the need of sustainable energy, health and aging population, climate change, sustainable production and working life, food production and clean water.

Science for Life Laboratory (SciLifeLab, http://www.scilifelab.se/ ) is a national center for large-scale life science research with an advanced technological infrastructure. At SciLifeLab, multidisciplinary research is carried out based on DNA sequencing, gene expression analysis, proteomics, bioinformatics, biostatistics and system biology. The goal is to enable Swedish researchers to analyze genes, transcripts and proteins in different organisms in order to map molecular mechanisms related to health and the environment. Examples of thematic research areas that are currently being processed within SciLifeLab are clinical genomics/proteomics, cancer genome and the genomics of complex diseases as well as ecological and environmental genomics.

Job description

Pelin Sahlén's lab studies functional differences between DNA sequence variants in disease and evolution context. We developed a method (HiCap) that provides high-resolution maps of regulatory interactions to find genes that are regulated by disease-related DNA sequence variants in different cell types. We have collected a very large amount of unique genetic and epigenetic data from several individuals and tissues; our goal is to integrate different layers of data to model how sequence variants alter certain processes related to heart disease.

We are looking for an outstanding postdoctoral researcher who shares our vision of translating knowledge of sequence variants into clinical applications. The successful candidate will be responsible for combining HiCap data from multiple tissues and individuals with other types of data. The project will include modeling and machine learning as well as handling and processing large amounts of interaction, sequence variations and epigenetics data.

What we offer

  • International workplace.
  • A leading technical university that creates knowledge and expertise for a sustainable future.
  • Here you get colleagues with high ambitions in an open, curious and dynamic environment.

Qualifications

Requirements

  • A doctoral degree in physics, biophysics, applied mathematics, computational biology or a related field (or an equivalent foreign degree), obtained within the last three years prior to the application deadline.
  • Excellent skills in English, both written and spoken

Great emphasis will be placed on personal competence and suitability.

Preferred qualifications

  • Big data analysis
  • Machine learning
  • Mathematical modeling
  • Bayesian statistical modeling and inference
  • Experience working within HPC environment
  • Programming skills in C++, Java or Python.
  • Scientific skills.
  • Educational ability.
  • Communication skills. 
  • Cooperative skills.
  • Independence. 

Trade union representatives

You will find contact information to trade union representatives at KTH's webbpage .

Application

Log into KTH's recruitment system in order to apply to this position. You are the main responsible to ensure that your application is complete according to the ad.

Your complete application must be received at KTH no later than the last day of application, midnight CET/CEST (Central European Time/Central European Summer Time).

Fixed term employment /temporary contract, no further than 28 02 2022.

About the employment

The position offered is for, at the most, two years.

A position as a postdoctoral fellow is a time-limited qualified appointment focusing mainly on research, intended as a first career step after a dissertation.

Others

Gender equality, diversity and zero tolerance against discrimination and harassment are important aspects of KTH's work with quality as well as core values in our organization.

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Disclaimer: In case of discrepancy between the Swedish original and the English translation of the job announcement, the Swedish version takes precedence.


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