Pharmacokinetic-pharmacodynamic modeling within oncology

Published: 2024-06-20

The Department of Pharmacy at Uppsala University has an interdisciplinary environment at the center of the pharmaceutical arena. With frontline research, first-rate education and extensive collaborations we constitute an important driving force in the development of our academic field. The department has approximately 150 employees and a turnover of approximately 140 million. We are looking for a postdoc in statistics/pharmacometrics.

In this inspiring environment our rich diversity of research groups, several of international prominence, develop and conduct work of great scientific importance. Among our core competences are pharmacokinetics-pharmacodynamics, computational modelling and simulations, in vitro ADME models, advanced in vivo methods, development of biological medicines, as well as patient and societal aspects, from optimizing the use of drugs in individuals to societal pharmaceutical policies. Together, we form a unique cluster of academic competences within pharmaceutical science, playing a key role in shaping the future of pharmacy in both Sweden and globally.

Our scientific focus areas in selection: Pharmacometrics • Pharmacodynamics • Pharmacokinetics • Biologics • Clinical Pharmacy • Drug Delivery • Molecular Pharmaceutics • Pharmaceutics and Nanotechnology • Pharmacoeconomics • Pharmacoepidemiology • Pharmacotherapy • Social Pharmacy

More information www.farmaci.uu.se

Duties
The project will involve development of pharmacokinetic (PK) and pharmacodynamic (PD) models for anticancer drugs. The developed models shall aim to characterize dose-exposure-response relationships of value for patient-specific dose optimization. We expect the project to lead to new advances in predictive and quantitative models of value for patients. The project may also include development of an application that can be used clinically.

Requirements
Eligible to be employed as a researcher is a person who has completed a PhD in pharmacokinetics/pharmacodynamics/pharmacometrics or a related field or has a foreign degree deemed to be equivalent to a doctorate in the specified fields. 

We place great emphasis on personal suitability and motivation to improve model-based methods for the development of individually tailored therapies against cancer. The applicant must be able to express him/herself well, both orally and in writing, in English.

Merits
Pharmacokinetic-pharmacodynamic modeling and simulation of therapies targeting cancer in children and/or adults. Experience of clinical work as well as of modeling in software such as NONMEM and R. Development of applications in e.g. Shiny. Interest in, and skill in, scientific writing is highly desirable, as is experience in international collaboration.

About the employment
The employment is a temporary position, 12 months. Scope of employment 100%. Starting date 15 September 2024 or as agreed. Placement: Uppsala

For further information about the position, please contact: Professor Lena Friberg, [email protected].

Please submit your application by 4 July 2024, UFV-PA 2024/2377.

Are you considering moving to Sweden to work at Uppsala University? Find out more about what it´s like to work and live in Sweden .

Uppsala University is a broad research university with a strong international position. The ultimate goal is to conduct education and research of the highest quality and relevance to make a difference in society. Our most important asset is all of our 7,600 employees and 53,000 students who, with curiosity and commitment, make Uppsala University one of Sweden’s most exciting workplaces.

Read more about our benefits and what it is like to work at Uppsala University
https://uu.se/om-uu/jobba-hos-oss/

The position may be subject to security vetting. If security vetting is conducted, the applicant must pass the vetting process to be eligible for employment.

Please do not send offers of recruitment or advertising services.

Submit your application through Uppsala University's recruitment system.

Placement: Department of Pharmacy

Type of employment: Full time , Special fixed-term employment

Pay: Individual salary

Number of positions: 1

Working hours: 100%

Town: Uppsala

County: Uppsala län

Country: Sweden

Union representative: Seko Universitetsklubben [email protected]
ST/TCO [email protected]
Saco-rådet [email protected]

Number of reference: UFV-PA 2024/2377

Last application date: 2024-07-04

Apply for position