The Department of Microbiology, Tumor and Cell Biology (MTC) at Karolinska Institutet in Stockhom conducts research and teaching in infection biology, immunology, cell biology and cancer. Our keywords are interdisciplinary, clinically based basic research and national and international cooperation.
Division
The research group of Dr Claudia Kutter seeks a Postdoc (either computational or computational/experimental) in the field of functional genomics and RNA biology. The Kutter lab has a track record in deciphering molecular mechanism by which RNAs (i.e. long noncoding, transfer and small RNA) regulate genes and genome structure in mammalian somatic tissue and in the germline (Geng et al. Genome Research 2022, Søndergaard et al. Gut, 2022, Gao et al. Genome Research 2022, Atanasoai et al. bioRxiv 2021). As a Postdoc in the Kutter lab you will be part of a multidisciplinary and collaborative research team active within the fields of RNA and chromatin biology, functional genomics and regulative transcriptomics.
The Kutter lab interrogates genome- and transcriptome-wide regulation and functionality by employing a combination of next generation sequencing technologies (both bulk and single-cell) and high-throughput genetic screening approaches, develops computational methods, along with applying experimental techniques. The group uses an integrative and collaborative approach, works closely with computational and experimental groups at KI, Science for Life Laboratory (SciLifeLab), and other local and international research groups. Frequent courses are provided on campus. Additional professional training is available through summer schools and recurrent workshops.
The laboratory is located at SciLifeLab on the Karolinska Institute campus in Stockholm. SciLifeLab offers an attractive research environment, provides state-of-the-art instrumentation and core facilities, and is home to the second largest sequencing cluster in Europe. SciLifeLab is a joint effort between Karolinska Institute, the Swedish Royal Institute of Technology, and Stockholm University. It hosts research groups with diverse backgrounds and expertise, creating a unique interface between basic biology, genomics, bioengineering, drug discovery, and translational medicine.
Duties
As a member of the Kutter lab, you will apply and optimize novel transcriptomic approaches (based on bulk and single cell RNA profiling) to study gene regulation and RNA processing using mammalian systems (primary tissues and cell lines), carry out validation experiments involving biochemical and molecular biological tools, and participate in the general duties of the team. As a Postdoc you will take a strong lead in the project design and management as well as data generation, analyses and interpretation, and collaborate with other team members. You are expected to report the scientific results by writing scientific papers, attending scientific meetings, and effectively communicate with peers. The ability to work in a highly interdisciplinary and international environment, and to engage in continuous professional development is a must.
Location: Solna, Science for Life Laboratory
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