Single Cell Genomics - Specialized Technician

Updated: over 1 year ago
Deadline: 06 Jul 2022

The Institute

The Centro Nacional de Análisis Genómico (CNAG-CRG) is one of the largest Genome Sequencing Centers in Europe. CNAG-CRG researchers participate in major International Genomic Initiatives such as the International Cancer Genome Consortium (ICGC), the International Human Epigenome Consortium (IHEC), the International Rare Diseases Research Consortium (IRDiRC) and the European Infrastructure for life-science information (ELIXIR), as well as in several EU-funded projects.

It is integrated with the Centre for Genomic Regulation (CRG), an international biomedical research institute of excellence, based in Barcelona, Spain, with more than 400 scientists from 44 countries. The CRG is composed by an interdisciplinary, motivated and creative scientific team which is supported both by a flexible and efficient administration and by high-end and innovative technologies.
In April 2021, the Centre for Genomic Regulation (CRG) received the renewal of the 'HR Excellence in Research' logo from the European Commission. This is a recognition of the Institute's commitment to developing an HR Strategy for Researchers, designed to bring the practices and procedures in line with the principles of the European Charter for Researchers and the Code of Conduct for the Recruitment of Researchers (Charter and Code).

Please, check out our Recruitment Policy

The role

The candidate will be integrated in the Single Cell Genomics Team, a highly collaborative, international work environment with well-experienced colleagues in single-cell data production and analysis. The candidate will be involved in the development, implementation and execution of single-cell and spatial sequencing applications. The candidate will be responsible to coordinate large-scale single-cell project production, including sample biobanking, data generation and documentation. The candidate will also be involved in collaborative efforts with our research and clinical partners and diverse production efforts of healthy and diseased human/mouse tissues.

The position is supported through EU-funded ERC and H2020 projects. The projects the candidate will be involved aim to understand the dynamics in B-cell maturation (ERC Synergy BCLLatlas project) and the molecular/cellular basis of immuno-therapy action by applying multi-omic single-cell and spatial characterisation of healthy and tumor microenvironment immune cells. The latter are obtained from clinical trials of immuno-therapy or advanced mouse model systems.

We are looking for a highly motivated and creative thinking individual who is interested in working in an environment where the technical sophistication of single-cell analysis meets innovative approaches for interpreting data and generating new knowledge. We encourage and prioritize applications from under-represented minority groups.

About the team

The Single Cell Genomics Team at the CNAG-CRG is dedicated to advance genome research of single cells. The mission of the group is the implementation of single-cell sequencing technologies and their application in a research and translational context. The group focuses on the systematic integration of transcriptional and epigenetic data from individual cells to elucidate causalities underlying phenotype formation. We successfully established sequencing protocols to quantify gene expression and open chromatin of thousands of single cells. Our newly developed computational pipelines include methods to deconvolute tissue composition and track to transcriptional dynamics. Our international team joins computational, technical and biological knowledge in order to establish and apply best practices in single-cell research. The group combines collaborative research, development activities and follows research lines on the generation of human cell atlases and on translational cancer research. We are member of the Human Cell Atlas Project.

Web: http://www.cnag.cat/teams/genome-research-unit/single-cell-genomics-team

Whom would we like to hire?

Professional experience

  Must Have

• You have strong expertise in single-cell and spatial genomics techniques
• You have training in next-generation sequencing library preparation
• You have more than 10 years of experience as a laboratory technician

Education and training

•  You hold a Bachelor in Science, Biology or related disciplines or “Cicle Formatiu de Grau Superior” in disciplines related to science

Languages

• You are proficient in English

Technical skills

• You have experience executing and coordinating large-scale data generation
• You have experience testing and implementing novel single-cell and spatial technologies
• You have experience with automation of single-cell production processes

Competences

• You have experience with large-scale project coordination
• You have problem solving skills
• You have organizational and time managment skills
• You are committed to high-quality work
• You have sound administrative abilities

The Offer

  • Contract duration: Contract linked to project duration (estimated 06/30/2025)
  • Estimated annual gross salary: Salary is commensurate with qualifications and consistent with our pay scales.
  • Target start date: July, 2022

We provide a highly stimulating environment with state-of-the-art infrastructures, and unique professional career development opportunities. To check out our training and development portfolio, please visit our website in the training section.

We offer and promote a diverse and inclusive environment and welcomes applicants regardless of age, disability, gender, nationality, ethnicity, religion, sexual orientation or gender identity.

The CRG is committed to reconcile a work and family life of its employees and are offering extended vacation period and the possibility to benefit from flexible working hours.

Application Procedure

All applications must include:

1. A motivation letter addressed to Dr Holger Heyn.
2. A complete CV including contact details.
3. Contact details of two referees.

All applications must be addressed to Dr. Holger Heyn and be submitted online on the CRG Career site http://www.crg.eu/en/content/careers/job-opportunities

Deadline: Please submit your application by July 6th, 2022.

Suggestions: The CRG believes in ongoing improvement and promotes a culture of feedback. This is one of the reasons we have in place, at your disposal as a candidate, a mechanism to gather your suggestions/complaints concerning your candidate experience in our recruitment processes. Your feedback really matters to us in our aim at creating a positive candidate journey. You can make a difference and help us improve by letting us know your suggestions through the following form.



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