Research Technician

The Institute

The Centre for Genomic Regulation (CRG) is an international biomedical research institute of excellence, based in Barcelona, Spain, with more than 400 scientists from 44 countries. The CRG is composed by an interdisciplinary, motivated and creative scientific team which is supported both by a flexible and efficient administration and by high-end and innovative technologies. 

The role  

We are seeking a highly motivated candidate to join our team to work on an interdisciplinary project. The candidate must be mastered several techniques, such as general DNA and RNA manipulation techniques purification, cloning, mutagenesis, NGS library preparation, PCR, RT-PCR, qPCR, chromatin Immunoprecipitation, proteomic techniques (protein extraction, subcellular fractionation, western blot, protein-protein interaction techniques), FACS and cell culture of primary and stablished cell lines. 

About the lab 

Understanding the genetic basis of cancers has been a topic of intense research, and hundreds of gene mutations have been identified that can cause carcinogenesis. However, in the past few years, increasing evidence has suggested that mutations are not the only genetic changes that lead to cancer. Indeed, perturbations of chromatin structure and of other epigenetic mechanisms can cause inappropriate gene expression and genomic instability, resulting in cellular transformation and malignant outgrowth.

Our research investigation is focused on understanding the role of several protein complexes that are involved in chromatin dynamics and metabolism, which when altered could participate in the establishment and maintenance of the aberrant silencing of tumour suppressor genes during transformation. 

Whom would we like to hire?  

Professional experience  

Must Have

• Previous experience in the field of molecular and cellular biology is required

• A highly motivated and organized candidate 

• Capable of working in a group, and with a high degree of work autonomy

Education and training

• You hold a PhD in Biology or equivalent 

Languages

• You are proficient in English 

Technical skills

• Molecular Biology (general DNA and RNA manipulation techniques including purification, cloning, mutagenesis, PCR, RT-PCR, qPCR)

• Chromatin Immunoprecipitation 

• Proteomic techniques (protein extraction, subcellular fractionation, western blot, protein-protein interaction techniques)  

• Cell culture of primary and stablished cell lines 

• Advance knowledge of bioinformatic analysis

Competences  

• Highly developed organization skills

The Offer – Working Conditions 

• Contract duration:1 year (part-time contract, 20 hours per week) with 2 additional years of extension, upon evaluation  

• Estimated annual gross salary: Salary is commensurate with qualifications and consistent with our pay scales

• Target start date:January 2023

We provide a highly stimulating environment with state-of-the-art infrastructures, and unique professional career development opportunities. To check out our training and development portfolio, please visit our website in the training section .

We offer and promote a diverse and inclusive environmentand welcomes applicants regardless of age, disability, gender, nationality, ethnicity, religion,sexual orientation or gender identity.

The CRG is committed to reconcile a work and family life of its employees and are offering extended vacation period and the possibility to benefit from flexible working hours.

Application Procedure

 All applications must include:

All applications must be addressed to Dr. Luciano Di Croce and be submitted online on the CRG Career site - through the "Apply" button below.  

Selection Process  

• Pre-selection: The pre-selection process will be based on qualifications and expertise reflected on the candidates CVs. It will be merit-based. 

• Interview: Preselected candidates will be interviewed by the Hiring Manager of the position and a selection panel if required. 

• Offer Letter: Once the successful candidate is identified the Human Resources department will send a Job Offer, specifying the start day, salary, working conditions, among other important details.  

Deadline: Please submit your application by December 30, 2022. 

Suggestions: The CRG believes in ongoing improvement and promotes a culture of feedback. This is one of the reasons we have in place, at your disposal as a candidate, a mechanism to gather your suggestions/complaints concerning your candidate experience in our recruitment processes. Your feedback really matters to us in our aim at creating a positive candidate journey. You can make a difference and help us improve by letting us know your suggestions through the following form.