Neuronal and Glial differentiation Specialist in the Tissue Engineering Unit

The Institute

The Centre for Genomic Regulation (CRG) is an international biomedical research institute of excellence, based in Barcelona, Spain, with more than 400 scientists from 44 countries. The CRG is composed by an interdisciplinary, motivated and creative scientific team which is supported both by a flexible and efficient administration and by high-end and innovative technologies.

In April 2021, the Centre for Genomic Regulation (CRG) received the renewal of the 'HR Excellence in Research ' Award from the European Commission. This is a recognition of the Institute's commitment to developing an HR Strategy for Researchers, designed to bring the practices and procedures in line with the principles of the European Charter for Researchers and the Code of Conduct for the Recruitment of Researchers (Charter and Code).

Please, check out our Recruitment Policy

The role

The desired candidate will be actively involved in the H2020 project entitled “Translational Platform for MSA: Elucidation of Disease-mechanisms and Drug discovery: TraP-MEDD” as part of an European consortium. For this project, the candidate will generate and characterize human iPS cells from MSA patient samples, will perform differentiation to neurons, astrocytes and oligodendrocytes that will be treated with distinct a-syn fibrillar strains. Further to that, a-syn fibrillar strain’s uptake, seeding, and accumulation propensities will be assessed in collaboration with international labs experts in the subject. The project will be done in close collaboration with experts in MSA disease and models from Fundacio Clinic per a la Recerca Biomedica (FCRB, Barcelona), Icahn School of Medicine at Mount Sinai (NYC, USA), CEA (France) and KU Leuven (Belgium). 

The candidate will form part of the Tissue Engineering team and will help in the achievement of specific goals. Applicants should be highly motivated, resolutive, methodological with accurate work habits and clear team-building skills. The ideal candidate has a strong ability to multi-task and has a service-oriented mentality. The position involves working some weekends and holiday days during the year.

The unit

The Tissue Engineering Unit is a technology unit within the Core Technologies Program. The goal of the Tissue Engineering Unit is to provide CRG, PRBB and external researchers with the latest technologies used in the fields of stem cell biology, stem cell differentiation, organoid formation, induced pluripotent stem cells (iPSCs) and CRISPR/Cas9 gene editing. The unit was established 5 years ago to help the research community in performing Stem Cell and Organoids projects and to perform technology development in the above fields.

Whom would we like to hire?

Professional experience

Must have

• You have 3 years’ experience in stem cell biology and ES/iPS cell differentiation systems
• You have 1 year experience in human iPS cell generation and characterization
• You have 3 years’ experience in hiPS cells neuronal/glial differentiation
• You have experience in organoids

Education and training

• You hold a Bachelor's degree in Biology or a related field and working experience in Stem Cell Biology/Neurobiology field.
• If you hold a Master/PhD’s degree in Stem cell Biology/Neurobiology will be considered a plus

Languages

• You are proficient in English
• You have a good level of Spanish

Technical skills

• You have a strong Tissue Culture experience for human ES/iPS cells
• You have experience in human ES/iPS cell neuronal/glial differentiation
• You have experience in human iPS reprogramming and human iPS cells quality controls
• You have experience with Immunofluorescence, confocal and FACS analysis for cellular characterizations

Competences

• You have highly-developed organizational skills
• You are capable of working in a group
• You have a high level of work autonomy
• You are communicative
• You are service-oriented

The Offer – Working Conditions

• Contract duration: 1 year with possibility of extension.
• Estimated annual gross salary: Salary is commensurate with qualifications and consistent with our pay scales.
• Target start date: Spring 2022.

We provide a highly stimulating environment with state-of-the-art infrastructures, and unique professional career development opportunities. To check out our training and development portfolio, please visit our website in the training section.

We offer and promote a diverse and inclusive environment and welcomes applicants regardless of age, disability, gender, nationality, race, religion or sexual orientation.

The CRG is committed to reconcile a work and family life of its employees and are offering extended vacation period and the possibility to benefit from flexible working hours.

Application Procedure

All applications must include:

1. A motivation letter addressed to Dr. Laura Batlle.
2. A complete CV including contact details.
3. Contact details of two referees.

All applications must be addressed to Dr. Laura Batlle and be submitted online on the "Apply" button below.

Selection Process

₋ Pre-selection: The pre-selection process will be based on qualifications and expertise reflected on the candidates CVS. It will be merit-based.

₋ Interview: Preselected candidates will be interviewed by the Hiring Manager of the position and a selection panel if required.

₋ Offer Letter: Once the successful candidate is identified the Human Resources department will send a Job Offer, specifying the start day, salary, working conditions, among other important details.

Deadline: Please submit your application by March 24 th, 2022.

Suggestions: The CRG believes in ongoing improvement and promotes a culture of feedback. This is one of the reasons we have in place, at your disposal as a candidate, a mechanism to gather your suggestions/complaints concerning your candidate experience in our recruitment processes. Your feedback really matters to us in our aim at creating a positive candidate journey. You can make a difference and help us improve by letting us know your suggestions through the following form.

“El presente contrato está financiado por fondos procedentes del proyecto AC21_2/00009 dentro del marco de la convocatoria 2021 de la Acción Estratégica en Salud 2017-2020 por la que se conceden subvenciones para Proyectos de programación conjunta internacional para las convocatorias trasnacionales FLAG-ERA”.