Clinical Data - AD-RIDDLE

8 Feb 2024
Job Information

Organisation/Company

BarcelonaBeta Brain Research Center

Department

Fluid Biomarkers and translational neurology

Research Field

Other

Researcher Profile

Recognised Researcher (R2)

Country

Spain

Application Deadline

8 Mar 2024 - 23:59 (Europe/Madrid)

Type of Contract

Other

Job Status

Full-time

Hours Per Week

38

Offer Starting Date

8 Feb 2024

Is the job funded through the EU Research Framework Programme?

Not funded by an EU programme

Is the Job related to staff position within a Research Infrastructure?

No

Offer Description

About the employer

The Barcelonaβeta Brain Research Center (BBRC) is a research center dedicated to the prevention of Alzheimer's disease and the study of cognitive functions affected in healthy and pathological aging. It was created in 2012 by the Pasqual Maragall Foundation, with the support of the Pompeu Fabra University.

The mission of the BBRC is to provide innovative solutions to decipher and prevent biological changes and cognitive dysfunction associated with neurodegenerative diseases. Due to the aging of the world population, these diseases constitute a global challenge, since for example, dementia can reach epidemic levels in 2050, with a forecast of more than 150 million people affected, if is not found a way to prevent its appearance and development.

The BBRC received the HR Excellence in Research award (HRS4R) granted by the European Commission; a recognition that shows its adherence to the principles of the European Charter for Researchers and the Code of Conduct for the Recruitment of Research Staff. The center offers a stimulating and favorable working environment in accordance with the Charter and Code, which describe the rights and responsibilities of researchers and their employers, and contributes to the creation of a transparent, attractive and open ecosystem at international level.

Pasqual Maragall Foundation, Pompeu Fabra University and “la Caixa” Foundation are permanent members of the BBRC Board. The center is affiliated and located in the Ciutadella Campus of the Pompeu Fabra University of Barcelona, in a building inaugurated in 2016. The BBRC headquarters has excellent technical facilities, including a 3TMR scanner dedicated to research, and spaces for conducting Clinical Trials and EEG. State-of-the-art scientific facilities, effective management and continuous high-standard peer-review evaluation are the BBRC core proceedings to ensure achieving world-class research results.

BBRC is also part of the Barcelona Biomedical Research Park (PRBB), a large research facility that hosts other seven different research institutions related to biomedical research, including the Center for Genomic Regulation (CRG), the Hospital del Mar Medical Research Institute (IMIM), the Department of Experimental and Health Sciences of the Pompeu Fabra University (CEXSUPF), the Institute of Evolutionary Biology (IBE CSIC-UPF), the Barcelona Institute of Global Health (ISGlobal) and the Barcelona site of the European Molecular Biology Laboratory (EMBL), among others, in a multidisciplinary, collaborative and stimulating international environment in close contact with a clinical setting, thus conducive to translational research.

For more information see: www.fpmaragall.org and www.barcelonabeta.org

 

About the job

BBRC is looking for a Clinical Data Analyst with a special interest in research and scientific tasks. This is a full-time position and the person selected will join the “fluid biomarkers and translational neurology” research group in the context of the European AD-RIDDLE project and will report to the “fluid biomarkers and translational neurology” Group Leader and the head of the Research Management Office at BBRC.

AD-RIDDLE is a European-funded multinational project that is set to revolutionize Alzheimer's Disease management in healthcare settings through its innovative toolbox platform. This initiative introduces community outreach tools for AD prevention awareness, incorporates clinically validated biomarkers for early AD detection (digital cognitive tools and Blood-based biomarkers), and will develop and validate algorithms to identify individuals who can benefit from new preventive therapies. AD-RIDDLE aims to simplify and enhance the detection, prevention, and treatment of AD, marking a significant advancement in healthcare practices.

The AD-RIDDLE Clinical Data Analyst will be responsible to manage, organize, harmonize the data of the real-world testing of blood-based biomarkers and digital cognitive assessments from the cohorts at BBRC. The Clinical Data Analyst will also participate in the development of predictive algorithms for early diagnosis, based on this data. The candidate will also coordinate the tasks of BBRC in this project and ensure that all the milestones are reached.

 

Main Responsibilities

The responsibilities for this position include:

● Develop a protocol to conduct real-world testing and analyses of data of digital cognitive biomarkers.

● Prepare the framework and develop a protocol for harmonised real-world testing of blood-based biomarkers across different clinical sites.

● Coordinate the prospective validation of blood-based biomarkers in early symptomatic patients and in preclinical AD; analyse and report the accuracy and robustness of the blood-based biomarkers.

● Assess the impact of blood-based biomarkers on the diagnostic work-up, compared by the “care-asusual”

● Prepare dataset to share with the study partners.

● Develop and implement monitoring and data quality control procedures.

● Participate, together with other study partners, in the development of a predictive algorithm for early diagnosis and decision support tool-kit to inform decision-making in early preventive therapies.

● Generate qualitative and quantitative reports.

● Perform scientific data analyses and support the project researchers.

● Write deliverables, scientific publications, etc.

 

Required qualifications and professional experience

● Bachelor or higher degree in Data Science, Biostatistics, Analytics or Big Data (this position could be covered by a postdoc with a PhD or could eventually allow the realization of a PhD within the ADRIDDLE project).

● Excellent written and oral communication skills in English.

● Expertise with clinical data

● Experience in the development of loading, cleaning and harmonization processes.

● Experience in integration and harmonization of clinical data.

● Experience in Data Mining and knowledge of data mining tools.

● Knowledge of programming languages

 

Personal skills

● High analytical abilities

● Team player attitude with internal as well as external collaborators.

● Attention to detail and accuracy.

● Organizational, time management and problem-solving skills.

● Self-initiative and adaptability to the dynamics and needs of the field.

● Strong interpersonal skills and ability to work effectively with a multidisciplinary team.

● Ability to think independently and work collaboratively (empathic and focused team- worker).

● Interest in joining a non-profit organization with a mission of high social impact.

 

We offer

● Starting date: ASAP 2024

● Salary will depend on skills/experience and will be in accordance to BBRC’s salary scales.

● The estimated duration of contract is 5 years, in line with the AD-RIDDLE project duration.

● Full time position, 38h per week.

● The Foundation offers an extended vacation period and the possibility of benefit from flexible working hours.

● Possibility of benefit from flexible working hours.

● Hybrid work model (on-site + teleworking) subject to the foundation’s regulations.

 

We offer and promote a diverse and inclusive environment and welcomes applicants regardless of age, disability, gender, nationality, ethnicity, religion, sexual orientation, or gender identity. A unique working opportunity in an international project. In the foundation, we also care about developing your professional career so you will participate in internal and specific training for your job, promotion opportunities and development of your professional career. We evaluate the potential of our team to develop those skills necessary to achieve a high level of professional performance.

 

Application process

To apply, please submit a single PDF file containing the following:

1) Cover letter describing research interests and relevant background;

2) CV

3) The names of up to three individuals who could provide reference letters.

All files or inquiries should be submitted electronically to: [email protected]

Requirements

Research Field

Computer science » Other

Education Level

Bachelor Degree or equivalent

Additional Information
Work Location(s)

Number of offers available

1

Company/Institute

BarcelonaBeta Brain Research Center

Country

Spain

State/Province

Barcelona

City

Barcelona

Postal Code

08005

Geofield

Where to apply

E-mail

[email protected]

Contact

State/Province

Barcelona

City

Barcelona

Website

https://www.barcelonabeta.org/

Street

Wellington, 30

Postal Code

08005

E-Mail

[email protected]

STATUS: EXPIRED