Bioinformatician in Epigenomics

The Institute

The Centre for Genomic Regulation (CRG) is an international biomedical research institute of excellence, based in Barcelona, Spain, with more than 400 scientists from 44 countries. The CRG is composed by an interdisciplinary, motivated and creative scientific team which is supported both by a flexible and efficient administration and by high-end and innovative technologies. 

In April 2021, the Centre for Genomic Regulation (CRG) received the renewal of the 'HR Excellence in Research ' Award from the European Commission. This is a recognition of the Institute's commitment to developing an HR Strategy for Researchers, designed to bring the practices and procedures in line with the principles of the European Charter for Researchers and theCode of Conduct for the Recruitment of Researchers (Charter and Code). 

Please, check out our Recruitment Policy

The role  

We are looking for an enthusiastic and motivated bioinformatician to join the Single Cell Epigenomics and Cancer Development lab to create a better understanding of the role of DNA methylation in gene regulation in healthy cells. The candidate will explore different types of (epi)genetic data, both in the context of individual projects as well as in collaboration with other team members.  

About the lab 

Different epigenetic layers regulate gene expression. In our lab, we aim to create a better understanding of how epigenetic events, in particular DNA methylation changes, arise and influence normal differentiation and non-Hodgkin lymphoma formation. To that end, we aim to study the occurrence of DNA methylation changes in healthy as well as in pre-malignant cells using bulk, single-cell and single-molecule data. On top of that, we aim to define related epigenetic events, such as enhancer activation and 3D chromatin interactions, that can influence the downstream effects related to the observed changes. Further information can be found at: https://www.crg.eu/en/programmes-groups/beekman-lab .

Whom would we like to hire?  

Professional experience  

Must Have

• You have at least 3 years of experience in analysing genome-wide (bulk, single-molecule and/or single-cell) data to explore DNA methylation 

• You have proven experience in NGS and genome-wide epigenetic data analysis

Desirable but not required/ Nice to have

• You master the analysis of other types of epigenetic data such as ATAC-seq, chIP-seq and 3D chromatin conformation capture data 

• You have experience in the analysis of single-cell data

Education and training

• You hold or are about to obtain a PhD degree in Computational Biology 

Languages

Technical skills

• Hands-on experience of at least 3 years in analysing genome-wide epigenetics and NGS data 

• You have advanced Unix operating systems skills 

• You are competent in Python, Perl and/or R 

Competences  

• Highly developed organization skills

• Excellent analytical and problem-solving skills

• Creativity allowing to explore data from unexplored angles

• Enthusiasm, motivation and dedication to explore new scientific avenues 

• Capability to work on different projects simultaneously as part of a team and/or independently 

The Offer – Working Conditions 

• Estimated annual gross salary: Salary is commensurate with qualifications and consistent with our pay scales 

• Target start date: September 1st 2024 

We provide a highly stimulating environment with state-of-the-art infrastructures, and unique professional career development opportunities. To check out our training and development portfolio, please visit our website in the training section .

We offer and promote a diverse and inclusive environmentand welcomes applicants regardless of age, disability, gender, nationality, ethnicity, religion,sexual orientation or gender identity.

The CRG is committed to reconcile a work and family life of its employees and are offering extended vacation period and the possibility to benefit from flexible working hours.

Application Procedure

All applications must include:

All applications must be addressed to Dr. R.Beekman and be submitted online throught the "Apply" button below.

Selection process

• Pre-selection: The pre-selection process will be based on qualifications and expertise reflected on the candidates CVS. It will be merit-based. 

• Interview: Preselected candidates will be interviewed by the Hiring Manager of the position and a selection panel if required. 

• Offer Letter: Once the successful candidate is identified the People department will send a Job Offer, specifying the start day, salary, working conditions, among other important details.  

Deadline: Please submit your application by 06/07/2024 

Contrato financiando con ayuda con referencia PID2021-123635NB-I00 financiado por MCIN/ AEI / 10.13039/501100011033 / FEDER, UE