Research Fellow (Mesenchymal Stem Cells) [LKCMedicine]

Research Fellow in Mesenchymal Stem Cells (MSCs) and Drug Discovery

Lee Kong Chian School of Medicine (LKC Medicine), a joint medical school between Imperial College London and Nanyang Technological University (NTU), is currently recruiting a Research Fellow to join the laboratory of A/Prof. Yen Choo. Our lab in the new Clinical Sciences Building, located in the heart of Singapore, is developing high-throughput platform technologies specifically for stem cell research.

There are different projects relating to MSCs namely in the field of bone and cartilage, and brown adipose tissue. These projects involve interdisciplinary research carried out in collaboration with government organisations and/or industrial partners. The successful candidate will have experience in cell-based assays, characterisation with molecular biological, and target-based drug discovery expertise.

Job responsibilities:

• To conduct molecular biology experimental procedures including DNA/RNA extraction, gene expression and RT-PCR, cell culture, tissue collection, cryosectioning and immunostaining

• Prepare and carry out experiments with MSCs

• Present experiment plans regarding target identification and validation

• Perform flow cytometry analysis and sorting

• Ability to operate confocal microscopy and others

• Perform laboratory administrative functions including procurement of laboratory inventories, replenishment of consumable materials and laboratory safety

• Coordinate laboratory meetings and seminars

• Perform basic bioinformatic research

• Preferably animal husbandry and maintenance

Competencies and Qualifications:

• PhD in relevant field of Stem Cell Biology, Molecular and Cell biology, Biochemistry, Biotechnology or related

• Outstanding track record in stem cell research

• Experience in MSCs culture, 3D cell culture techniques and cell-based assays

• Wide repertoire of current cell and molecular biology methodology (immunofluorescence microscopy, transfection, etc)

• Experience in target-based drug discovery is highly desirable

• Knowledge of biochemical basics, analytical skills and assay design and statistics

• Grant writing experience desirable

• Exposure to industry desirable

• Organized, motivated, self-driven, team player and reliable.

• Adaptable in a rapidly changing research environment.

Hiring Institution: LKC