Imaging & Characterization Core Lab - CryoEM Staff Scientist

Position Summary :

• The individual serves the IAC mission to support research at KAUST and regionally by providing techniques and expertise for advanced and routine electron microscopy analysis in a user- driven environment.
• The scientist serves this mission in his/her main area of expertise, which is Cryo electron microscopy.
• This position is with a focus on Cryo EM in life science that includes plant biology, STEM cell research and marine biology.
• Independently applies advanced knowledge in Cryo EM to solve related question in the field of cell biology.
• Devises new approaches to problems encountered in plant and marine biology and in the field of STEM cell research.
• Works on problems of diverse scope and offer a technical solution to relevant projects within the biology division.

Major Responsibilities :

• Work in a team of scientists to build up technical expertise in 3D Cryo electron microscopy, including single particle analysis and cryo tomography imaging.
• Train users and scientist on advance techniques of Cryo EM, Cryo tomography and sub tomogram averaging.
• Perform and train users on reliable Cryo-EM sample preparation including cryo FIB.
• Work on methodology development for continuous resolution improvement, including associated Standard Operating procedures (SOP).
• Engage in KAUST research projects that require advanced Cryo electron microscopy techniques to facilitate high impact research.
• Keep up to date on the latest development in in the area of Cryo electron microscopy.
• Maintain and run EM sample preparation Lab.
• Ensure good laboratory practice and safety in the assigned work area at all times
• Ensure maximum uptime of assigned instruments (plan and oversee preventative and corrective maintenance, purchase consumables, etc.)
• Perform routine laboratory duties and maintenance, including administrative, procurement, service on task forces and committees
• Develops and evaluates plans and criteria for a variety of projects and activities to be carried out by others
• Organizes and chairs sessions at technical meetings; presents invited papers; primary author or key contributor on major reports, products, papers, presentations, and peer reviewed journals.
• Other duties as assigned by the Team Lead and Lab Director

Competencies :

• Demonstrable expertise in Cryo electron microscopy, including EM Cryo sample preparation, Cryo EM imaging, 3D tomography and single particle analysis and sub tomogram averaging.
• Solid foundation of structural biology.
• Capability to plan and conduct work requiring independent judgment in the evaluation, selection, and substantial adaptation/modification of standard techniques
• Some organizational skills as well as ability to work effectively and efficiently in a multi-cultural environment, and collaborate with team members, lab users, and external service providers.
• Ability to interpret and determine validity of data and contribute to written and oral presentations related to research findings.
• Ability to effectively supervise and train staff

Qualifications/Experience :

• Ph. D degree in Life Sciences or related field
• Extended experience (minimum 3 years) in Cryo TEM/SEM.
• Solid knowledge in structural biology and single particle Cryo EM workflow (experience in Cryo electron tomography is a plus).
• Publication record showing the acquired experience in Cryo EM.