Postdoctoral position in biological chemistry & enzymology at Babes-Bolyai University

Updated: about 2 months ago
Job Type: FullTime
Deadline: 15 Apr 2024

27 Feb 2024
Job Information
Organisation/Company

Babes-Bolyai University
Department

Department of Chemistry
Research Field

Chemistry » Biochemistry
Researcher Profile

Recognised Researcher (R2)
Country

Romania
Application Deadline

15 Apr 2024 - 00:00 (Europe/Bucharest)
Type of Contract

Temporary
Job Status

Full-time
Hours Per Week

40
Offer Starting Date

1 May 2024
Is the job funded through the EU Research Framework Programme?

Not funded by an EU programme
Is the Job related to staff position within a Research Infrastructure?

No

Offer Description

The postdoctoral contract can start from April-May 2024 at the Enzymology and Applied Biocatalysis Research Center  from Babes-Bolyai University for a period of 1+ 1 (extension possibility) year. Gross salary will range from 2900 to 3500 EUR depending on the experience of the candidate.

Applications: Candidates with Ph.D degree and expertise related to enzymology, chemical biology are encouraged to apply. Strong experience in high-throughput enzyme assay development, recombinant protein expression/purification, protein-ligand interaction measurements are required. Strong motivation, intellectual curiosity, communication skills (written and spoken – English) are mandatory.

The research project: asim to develop novel antimicrobial agents by exploring the structural facets and modulation/inhibition of enzymes involved in bacterial protein-protein interactions (PPIs), essential for the assembly and integrity maintenance of bacterial cell envelope. The complex multilayered bacterial cell membrane, with its unique and essential structural components, provides several specific targets for antibiotic drug development. The project employs novel state-of-art methodologies, such as fragment-based ligand discovery by X-ray crystallography and 19F-NMR techniques, high-throughput and virtual ligand screenings, for the discovery of hits targeting rigorously selected bacterial PPIs, followed by their in vitro/in vivo validation.

The postdoctoral fellow will work in close relationship with Assoc. Prof. Dr. Laszlo Csaba Bencze , the institutional coordinator of the project.

 


Requirements
Research Field
Chemistry » Biochemistry
Education Level
PhD or equivalent

Skills/Qualifications

Candidates with Ph.D degree and expertise related to enzymology, chemical biology are encouraged to apply. Strong experience in high-throughput enzyme assay development, recombinant protein expression/purification, protein-ligand interaction measurements are required. Strong motivation, intellectual curiosity, communication skills (written and spoken – English) are mandatory.


Languages
ENGLISH
Level
Good

Research Field
Chemistry » BiochemistryBiological sciences » Biological engineering
Years of Research Experience
4 - 10

Additional Information
Selection process

selection by on-line interview and CV, motivation letter


Work Location(s)
Number of offers available
1
Company/Institute
Babes-Bolyai University, Enzymology and Applied Biocatalysis Research Center
Country
Romania
State/Province
Cluj
City
Cluj-Napoca
Postal Code
RO-400028
Street
Str. Arany Janos, nr.11
Geofield


Where to apply
E-mail

[email protected]

Contact
City

Cluj-Napoca
Website

https://chem.ubbcluj.ro/BIO/CENTRU/indexen.php
Street

Arany Janos 11
Postal Code

400028
E-Mail

[email protected]

STATUS: EXPIRED

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