001/BI/2024 - Fellowship for Masters

8 Jan 2024
Job Information

Organisation/Company

Instituto de Tecnologia Química e Biológica António Xavier ITQB NOVA

Research Field

Biological sciences » Biology
Chemistry » Biochemistry

Researcher Profile

First Stage Researcher (R1)

Country

Portugal

Application Deadline

18 Jan 2024 - 13:59 (Europe/Lisbon)

Type of Contract

To be defined

Job Status

Full-time

Hours Per Week

35

Offer Starting Date

5 Jan 2024

Is the job funded through the EU Research Framework Programme?

Not funded by an EU programme

Reference Number

001/BI/2024

Is the Job related to staff position within a Research Infrastructure?

No

Offer Description

Instituto de Tecnologia Química e Biológica António Xavier
Application for a Research Fellowship
within the project HR22-00722

Applications are invited for a Master Fellowship in the scope of the project entitled “The BioPlaTTAR Platform for the Tailored and Rapid Development of Antiviral Biopharmaceuticals”, reference HR22-00722, funded by “La Caixa” Foundation and by Fundação para a Ciência e a Tecnologia I.P./MCTES, through national funding (PIDDAC).

Main Scientific Areas & Sub-Research Fields: Biology Sciences – Biochemistry; Structural Bioinformatics
 
Academic degree: We are seeking candidates with a Master's degree in Biopharmaceutical Sciences or related areas (i.e., Biology, Biomedicine, Biophysics, Chemistry etc.) with a bachelor’s degree classification of 17 (or higher) and a master’s degree classification of 19 (or higher).
 
Other requirements:
●    Experience in the application of molecular dynamics simulations to the study of proteins from SARS-CoV-2 and its variants;
●    Experience with the molecular modeling and visualization software packages GROMACS, MDAnalysis, PyMOL and Alphafold2;
●    Experience in LINUX operative systems;
●    Experience in developing scripts using Bash and Python programming languages;
●    Experience in protein expression and purification;
●    Experience in biophysical characterization techniques, specifically Circular Dichroism, Dynamic Light Scattering and Differential Scanning Fluorimetry;
●    Being enrolled in a non-academic degree course (by the time of the contract signature) or in a Ph.D., in accordance with the Article 6th of “Regulamento de Bolsas de Investigação da Fundação para a Ciência e a Tecnologia, I.P.”, law in force (Mandatory).

Working Plan: The successful candidate will participate in the implementation of the platform for the computational design of antiviral proteins and the characterization of their biological behavior through molecular dynamics simulation. The structural dynamics of the interaction between the design proteins and the target viral proteins will also be evaluated.  Additionally, the candidate will express, purify and characterize the most promising proteins obtained in the computational design, as well as join in the development of an algorithm for the prediction of viral variants.

Applicable Law and Regulations: Status of Scientific Research Fellow, approved by Law number 40/2004, of August 18th, changed and republished by Ordinance 202/2012 of August 27th and changed by Ordinance 233/2012 of October 29th and by Law 12/2013 of January 29th and by Ordinance 89/2013 of July 9th and by the Ordinance 123/2019 of August 28th;
Regulations for Research Fellowships from Fundação para a Ciência e a Tecnologia, I.P., in force (https://www.fct.pt/apoios/bolsas/docs/RegulamentoBolsasFCT2019.pdf ).

Working Place: The work will be carried out in the Protein Modeling Lab and Applied Protein Biochemistry Lab at ITQB NOVA under the supervision of Professor Cláudio Soares, Doctor Diana Lousa and Doctor João Vicente.

Duration of the fellowship: The fellowship will have a duration of 6 months, eventually renewable, expected to start in February 2024, on a full-time basis, according to Fellowship Regulations of Fundação para a Ciência e Tecnologia, I.P.

Stipend amount: EUR 1199,64 €, according to the table of values of grants awarded directly by the FCT, I.P. in the Country (https://www.fct.pt/wp-content/uploads/2023/02/Tabela-de-Valores-SMM_202… ) and payment will be made, monthly, through bank transfer.

Selection procedure: The evaluation procedure will be primarily based on analyzing the candidates´ CVs and, if necessary, an interview with the selected candidates may occur. In this case, the CV evaluation and the interview will have weights of 50% each.

Jury composition: Doctor Diana Lousa (President), Professor Cláudio M. Soares (effective member), Doctor João B. Vicente (effective member); Doctor Manuel N. Melo (substitute member).

Application documents: The application should be formalized by sending by e-mail (to [email protected] ) as a single PDF file containing the following documents: i) a cover letter indicating the corresponding fellowship reference; ii) motivation letter including the names and e-mail addresses of two possible references; iii) detailed Curriculum Vitae; iv) degree certificate. If the degree has been conferred by a non-Portuguese higher education institution, the selected candidate must obtain the certificate of degree recognition, issued by the Portuguese Directorate General for Higher Education or by a Portuguese Public Higher Education Institution, until the signature of the contract. Regarding this issue, please consult the website of the Portuguese Directorate General for Higher Education: https://www.dges.gov.pt/en .

Notification of candidates: All the candidates will be informed of the final result by e-mail.

Deadlines and procedures for complaints and appeals: The candidates that were not selected have a period of 10 working days, after the disclosure Applicable Law and Regulations: Status of Scientific Research Fellow, approved by Law number 40/2004, of August 18th, changed and republished by Ordinance 202/2012 of August 27th and changed by Ordinance 233/2012 of October 29th and by Law 12/2013 of January 29th and by Ordinance 89/2013 of July 9th and by the Ordinance 123/2019 of August 28th;

Application period: From 5 to 18 of January 2024

Applications should be sent to:
Doctor Diana Lousa
Email: [email protected]
Ref. 001/BI/2024
OEIRAS

 

Requirements

Research Field

Biological sciences » Biology

Education Level

Master Degree or equivalent

Additional Information
Work Location(s)

Number of offers available

1

Company/Institute

ITQB NOVA

Country

Portugal

State/Province

Oeiras

City

Oeiras

Postal Code

2780-156

Street

Av da Republica, INIAV

Geofield

Where to apply

E-mail

[email protected]

Contact

State/Province

Lisboa

City

Oeiras

Website

http://www.itqb.unl.pt/

Street

Av. da República, E.A.N

Postal Code

2780-156

E-Mail

[email protected]

STATUS: EXPIRED