Postdoctoral researcher

Updated: 3 months ago
Job Type: FullTime
Deadline: 18 Feb 2024

22 Jan 2024
Job Information

The International Institute of Molecular Mechanisms and Machines Polish Academy of Sciences
Research Field

Biological sciences » Biology
Researcher Profile

Recognised Researcher (R2)

Application Deadline

18 Feb 2024 - 23:59 (Europe/Warsaw)
Type of Contract

Job Status

Hours Per Week

Offer Starting Date

1 Mar 2024
Is the job funded through the EU Research Framework Programme?

Not funded by an EU programme
Reference Number

Postdoc Opus MC 01 2024
Is the Job related to staff position within a Research Infrastructure?


Offer Description

About IMol:

The International Institute of Molecular Mechanisms and Machines (IMol) Polish Academy of Sciences, was constituted in December 2020, in partnership with University Medical Center Göttingen, Germany and University of Warsaw, Poland. IMol has been established to conduct scientific research and provide training in the fields of biological, chemical, medical, biotechnological, bioinformatics, biophysical, pharmacological, and similar sciences, in the international environment conducive to collaborative efforts, research and development interactions with biotechnological industry, and wide dissemination of our results. We aim at the development of solutions that will help everyone on this planet live a safer life.

About the job:

Currently IMol is seeking for highly motivated candidates for a position of: 1 Postdoc in Dr Maciej Cieśla group

Our group is interested in understanding how RNA metabolism is integrated during early steps of stem cell activation. We use different types of cellular and tissue systems as a test tube to understand the dynamics of functional coordination of macromolecular machinery of the spliceosome. Collectively, we want to understand regulation of splicing when stem cells decide their fate between self-renewal and differentiation. Key responsibility of the successful candidate will be to delineate dependencies in spliceosome composition-to-function upon exit from stemness of hematopoietic stem cells, and to study impact of differential splicing on selection of differentiation trajectories during blood differentiation. These goals will be achieved by applying state-of-the-art techniques available in the lab, including CRISPR-Cas9 genome editing, high-throughput profiling of transcriptomes and translatomes, molecular biology assays, bioinformatic analysis, and primary cell cultures in vitro and in vivo. We particularly encourage applications from candidates with a computational biology background and/or strong track in in vivo approaches. Prior expertise in stem cell biology, including hematopoiesis, will be considered a strong asset.

More about the research group:
More about the project:

Profile of candidates/requirements:

  • PhD in cell biology, molecular biology, biochemistry, or related fields (obtained after 2020). Candidates with planned PhD defense in early 2024 are eligible to apply.
  • Very well-structured knowledge in cell biology and biochemistry
  • Previous hands-on training in molecular biology, cell biology or biochemistry lab
  • Good command of English is essential
  • Previous experience with primary mammalian cell culture and computational analysis will be advantageous but is not obligatory
  • Interest to develop own lines of research
  • Good communication skills

Key responsibilities:

  • Planning and performing experiments
  • Keeping a record of experimental details
  • Data analysis, including bulk and single cell RNA sequencing, results interpretation and discussion
  • Presenting results at internal and external meetings/conferences
  • Preparing manuscripts for publication in scientific journals
  • Active participation in the research conducted in the lab.

We offer:

  • Start date: March 2024 or later upon agreement.
  • Full-time position for up to 5 years. Initial contract signed for 6 months.
  • Salary of ca. 6.900 PLN net/month
  • Medical care package and social benefits
  • Flexible working hours
  • Collaborative and supportive work culture
  • Participation in an ambitious interdisciplinary project
  • Working with state-of-the-art research equipment
  • Opportunity to gain unique professional experience

How to apply:

Please apply by filling in this form:
You will be asked to attach the following documents – please combine them into 1 PDF document

Required documents (in English):

  • Motivation letter;
  • CV;
  • A list of publications and conferences attended;
  • Contact details to a person who can provide references (preferably PhD supervisor).

    Research Field
    Biological sciences » Biology
    Education Level
    PhD or equivalent

    Additional Information
    Work Location(s)
    Number of offers available
    IMol PAS

    Where to apply





    Flisa 6
    Postal Code



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