Postdoctoral researcher

About the job

The International Institute of Molecular Mechanisms and Machines (IMol) Polish Academy of Sciences, was constituted in December 2020, in partnership with University Medical Center Göttingen, Germany and University of Warsaw, Poland.

IMol has been established to conduct scientific research and provide training in the fields of biological, chemical, medical, biotechnological, bioinformatics, biophysical, pharmacological, and similar sciences, in the international environment conducive to collaborative efforts, research and development interactions with biotechnological industry, and wide dissemination of our results.

Currently IMol is seeking for highly motivated candidates for a position of:

POSTDOC in OPUS 18 project – dr Michał Wasilewski

A few words about the research group:

Laboratory of Mitochondrial Biogenesis led by Prof. Agnieszka Chacińska is a research group with an excellent publication record in molecular cell biology. We are interested in fundamental cellular mechanisms in physiology as well as in pathology and ageing. Our research is focused on mechanisms of protein import to mitochondria and on the cellular response to dysfunction of these mechanisms. We use diverse model systems such as human cells, yeast, fish Danio rerio and worm Caenorhabditis elegans.

Project leader: Michał Wasilewski, PhD

Project title: “Mitochondrial import pathways of viral proteins.”

Project description:

Mitochondria are a vital intersection of multiple metabolic pathways and an information platform that integrates signaling for apoptosis and the innate immunity. Therefore it is not surprising that multiple viruses trim functions of mitochondria to their own needs. In some cases this interaction requires import of viral proteins to mitochondria but molecular mechanisms of these phenomena remain poorly understood. We plan to explore and characterize mechanisms of translocation of viral proteins to mitochondria.

Description of your tasks:

- Performing experiments using biochemical, cell and molecular biology techniques (independently and in collaboration with other team members)

- Designing experiments and analysing data

- Writing manuscripts

- Participation in supervision of MSc and PhD students

- Participation in preparation of grant applications

- Active participation in lab meetings, scientific seminars and conferences