Postdoctoral researcher – Laboratory of Stem Cell RNA Metabolism (# of pos: 2)

The International Institute of Molecular Mechanisms and Machines (IMol) Polish Academy of Sciences, was constituted in December 2020, in partnership with the University Medical Centre Göttingen, Germany and the University of Warsaw, Poland. IMol has been established to conduct scientific research and provide training in the fields of biological, chemical, medical, biotechnological, bioinformatics, biophysical, pharmacological, and similar sciences, in the international environment conducive to collaborative efforts, research and development interactions with the biotechnological industry, and wide dissemination of our results. We aim at the development of solutions that will help everyone on this planet live a safer life.

Currently, IMol is seeking highly motivated candidates for the position of Postdoctoral researcher

Our group is interested in understanding how RNA metabolism is integrated during the early steps of stem cells activation. We use the hematopoietic system as a test tube to look at the coordination of macromolecular machinery of the spliceosome, once stem cells decide their fate between self-renewal and differentiation. The key responsibility of the successful candidate will be to delineate changes in spliceosome composition and function upon exit from quiescence and to study the effects of differential splicing on how the stem cells select their differentiation trajectories. We particularly encourage candidates with a computational biology/bioinformatics background. Good command in performing primary cell cultures will be considered a strong asset.

We offer:

• Start date: 11 2022
• Full-time position for up to 4 years
• Salary of ca. 6.000 PLN net/month
• Medical care package and social benefits
• Flexible working hours
• Collaborative and supportive work culture
• Participation in an ambitious interdisciplinary project
• Working with state-of-the-art research equipment
• Opportunity to gain unique professional experience

Key responsibilities:

• Planning and performing experiments
• Keeping a record of experimental details
• Data analysis, including bulk and single cell RNA sequencing, results interpretation and discussion
• Presenting results at internal and external meetings/conferences
• Preparing manuscripts for publication in scientific journals
• Active participation in the research conducted in the lab.

Profile of candidates/requirements:

• PhD project in cell biology, molecular biology, biochemistry, or related fields
• Very well-structured knowledge in cell biology and biochemistry
• Previous hands-on training in molecular biology, cell biology or biochemistry lab
• Good command of English is essential
• Previous experience with primary mammalian cell culture and computational analysis would be advantageous but is not obligatory
• Good communication skills

Required documents (in English):

• Cover letter
• CV
• List of publications
• Reference contacts (please do not send generic letters, contact details only)

If you think you are the person who we are looking for, please apply by filling in this form: https://forms.gle/Exoy7iw4U8cYLL9C6