The Nencki Institute of Experimental Biology PAS is seeking a candidate for the position of:
Postdoctoral Researcher at the Laboratory of Protein Homeostasis
Place of work: Laboratory of Protein Homeostasis
Type of recruitment: NCN SONATA BIS: Ubiquitin as a modulator of the mitochondrial protein import process
Scope of the project:
Protein transport and degradation are vital mechanisms that maintain the homeostasis of the cell. The project investigates how these mechanisms integrate into the biogenesis of mitochondrial proteins. Most mitochondrial proteins are produced in the cytosol and require active transport into the organelle. Such proteins require efficient regulation and quality control before they enter mitochondria. The cytosolic ubiquitin-proteasome system plays such a regulatory role. The project's main objective is to uncover how different proteins directed to mitochondria are affected by ubiquitination. We will also identify the factors that regulate this process at the molecular level and reveal their role in physiology and pathology.
The study uses cellular and in-vitro models. You will have an opportunity to use human cell cultures, yeast Saccharomyces cerevisiae, and in-vitro protein synthesis, all combined with advanced molecular and cell biology techniques, including mass spectrometry proteomics, FACS, and confocal microscopy.
Key responsibilities of the Postdoctoral Researcher include:
Designing, performing, and interpreting experiments.
Data presentation and preparation for publication.
Active participation in laboratory meetings, scientific seminars, and conferences.
Similar Positions
-
Postdoctoral Position In Bacterial Cell Wall Biology And Genetics , Umeå University, Sweden, about 15 hours ago
Umeå University is one of Sweden’s largest higher education institutions with over 37,000 students and about 4,700 employees. The University offers a diversity of high-quality education and world-...
-
Postdoctoral Fellow Structural Biology And Vaccine Development, City of Hope, United States, about 8 hours ago
Join the forefront of groundbreaking research at the Beckman Research Institute of City of Hope , where we're changing lives and making a real difference in the fight against cancer, diabetes, and...
-
Postdoctoral Researcher In Decoding Splicing Codes Of The Brain, Karolinska Institutet, Sweden, about 2 hours ago
Do you want to contribute to top quality medical research? A postdoctoral research position is available in the lab of Rickard Sandberg at the institution for Cell and Molecular Biology (CMB). The...
-
Postdoctoral Fellow Hematological Malignancies And Translational Sciences, City of Hope, United States, about 8 hours ago
Join the forefront of groundbreaking research at the Beckman Research Institute of City of Hope, where we're changing lives and making a real difference in the fight against cancer, diabetes, and...
-
Postdoctoral Researcher In Structural Biology, University of Helsinki, Finland, 2 days ago
Postdoctoral Researcher in Structural biology of innate immune response in modulation of neuronal synapse loss in Alzheimer’s disease/neurodegeneration The HiLIFE - Institute of Biotechnology at t...
-
Postdoctoral Researcher In Structural Biology, University of Helsinki, Finland, about 14 hours ago
Postdoctoral Researcher in Structural Biology of innate immune response in modulation of neuronal synapse loss in Alzheimer’s disease/neurodegeneration The HiLIFE - Institute of Biotechnology at t...