Postdoctoral researcher

Adam Mickiewicz University, Poznań, Poland

Updated: about 2 years ago
Job Type: FullTime
Deadline: 31 Mar 2022

The recently created Functional Genomics Laboratory led by Dr Magdalena Masłoń at the Adam Mickiewicz University in Poznań, Poland seeks a motivated candidate to join as a postdoctoral researcher.

About the project.

Normal cellular processes rely on precise coordination of gene transcription, whereas disruption of this process underlies numerous developmental defects and diseases, including cancer. RNA Polymerase II (RNAPII) is the key enzyme involved in gene transcription, the process whereby nascent protein-coding and non-coding RNAs are produced.

The broad goal of our research is to understand how gene expression is controlled during development and in homeostasis, and how this regulation changes over the life course or in disease states. More specifically, we are studying the transcription kinetics in the context of neurodevelopment and genome stability. The project is generously supported by NCN funding (SONATA BIS project 2020/38/E/NZ1/00070).

About your position and the project.

You will apply genome editing and various high-resolution multi-omics methods to pluripotent stem cells-based models to unravel the role of RNAPII elongation rate control and the consequences of its perturbation in development.


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