assistant professor

Current research program of the Laboratory of Immunology.

The research topics of the Laboratory of Immunology include cancer immunology, mechanisms regulating the activation of cells of the immune system, cancer immunotherapy with the use of monoclonal antibodies, NK cells and the effector cells modified with chimeric antigen receptors. We conduct basic as well as translational research to use our findings in the development of new therapies.

The area of the research in which the candidate would participate.

Therapy with chimeric antigen receptors (CAR)-modified T cells recognizing the CD19 antigen is extremely effective in the treatment of lymphomas and acute lymphoblastic leukemia. Nevertheless, due to the increasing number of reports on the emergence of resistance to CD19-targeing CAR-T therapies, intensive research is conducted to identify new therapeutic targets. One of the mechanisms of resistance to CAR-T therapy is the reduction in the levels of CD19 protein in the membrane of cancer cells. In this project, we will focus on characterizing the changes that occur in B-cell neoplasms due to the depletion of the CD19 protein. The results of this project will not only provide new insight into the biological role of the CD19 protein, but will also identify new therapeutic options for patients refractory to CAR-T therapies recognizing CD19 antigen.

Description of job position activities:

• conducting scientific research in accordance with the current research topic of the Laboratory of Immunology,
• applying for external funding of research projects,
• introducing new research technologies to improve the quality of scientific research,
• active participation in the Laboratory's scientific seminars,
• representing the Laboratory at national and international scientific conferences,
• active publication of research results.

Requirements for the position of assistant professor:

• minimum a PhD degree in medical or related sciences,
• at least, 2 publications in scientific journals with impact factor, of total IF ≥ 6, including at least 1, in which the candidate is the first, equivalent to the first or corresponding author, published after the Doctorate, but not containing the results of the Doctorate,
• at least 2 publications in scientific journals with impact factor IF, in which the candidate is the first or corresponding author,
• completion of a minimum 3-months postdoctoral training in the scientific institution other than Mossakowski Medical Research Institute, Polish Academy of Sciences,
• experience in application for research funding and managing research projects,
• documented active participation in national and international conferences and symposia,
• fluency in English.

Additional requirements (desirable):

• scientific achievements - having more than the required number of scientific publications in scientific journals with IF, with a high total IF, including those in which the candidate is the first or corresponding author,
• experience in organizing scientific conferences and events aimed at popularizing science.

We offer:

• employment contract (part-time),
• access to specialized equipment in the Institute,
• possibility to participate in running research projects in the Laboratory of Immunology,
• the possibility of scientific development,
• possibility of additional training (also abroad),
• friendly work environment and teamwork.