9 Feb 2024
Job Information
- Organisation/Company
Warsaw University of Technology- Research Field
Biological sciences » Biology
Chemistry » Biochemistry
Engineering » Biomedical engineering- Researcher Profile
Recognised Researcher (R2)- Country
Poland- Application Deadline
10 Mar 2024 - 16:00 (Europe/Warsaw)- Type of Contract
Temporary- Job Status
Full-time- Hours Per Week
40- Is the job funded through the EU Research Framework Programme?
Not funded by an EU programme- Is the Job related to staff position within a Research Infrastructure?
No
Offer Description
The research topics will be related to the implementation of the project: “Development of a microfluidic model of the blood-brain barrier to study changes in its permeability using electroporation - a new tool for assessing the effectiveness of therapeutic procedures used in neurodegenerative diseases”. In vitro models obtained using microfluidic systems can be a useful tool in examining changes in the permeability of the blood-brain barrier, because it is quite easy to obtain a microenvironment in them that mimic in vivo conditions. Additionally, application of microsystems in in vitro research allow to eliminate variable conditions, that occur during animal research. The aim of the research will be to develop a model of the blood-brain barrier enabling real-time measurement of changes in its permeability as a result of the application of electrical impulses (using an electric field to change the integrity of the blood-brain barrier).
This work will include:
- development of a microsystem design for testing the assisted transport of compounds across the blood-brain barrier;
- selection of materials and methods of microsystem fabrication;
- selection of electroporation parameters carried out in a microsystem based on the blood-brain barrier model;
- development of methods for visualization and quantitative analysis of compound transport;
- study of the transport of selected compounds used in the treatment of neurodegenerative diseases.
Requirements
- Research Field
- Technology » Biotechnology
- Education Level
- PhD or equivalent
Skills/Qualifications
The candidate should have a PhD degree in biology, biotechnology or related field. The candidate is expected to have experience in at least two of the research directions listed below:
- research conducted on various types of cell cultures;
- fluorescent and immunofluorescent staining of cells and their microscopic observation;
- conducting biological tests used to assess the viability and metabolic activity of cells;
- conducting research with lab-on-a-chip systems.
His/her scientific achievements should be documented by the authorship of papers related to the profile of the announced research position. Capability of leading independent research activity is a necessary.
- Languages
- ENGLISH
- Level
- Excellent
- Languages
- POLISH
- Level
- Excellent
- Years of Research Experience
- 1 - 4
Additional Information
Additional comments
Ilona Grabowska-Jadach D.Sc., M.Sc., Eng., Gmach Chemii, ul. Noakowskiego 3, 00-664 Warszawa, e-mail: [email protected]
Work Location(s)
- Number of offers available
- 1
- Company/Institute
- Faculty of Chemistry, Chair of Medical Biotechnology
- Country
- Poland
- City
- Warsaw
- Postal Code
- 00-664
- Street
- Noakowskiego 3
- Geofield
Where to apply
[email protected]
Contact
- City
Warsaw- Website
http://www.pw.edu.pl- Street
Plac Politechniki 1- Postal Code
00-661
[email protected]
STATUS: EXPIRED
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