The objective of the overall project is to reveal the regulatory role of autoimmune risk variants in human thymic antigen presenting cells by cellular, transcriptomic and epigenetic characterization of existing cell populations in the human thymus. Next, the correlations between risk alleles and expression profiles, alternative splicing and the binding of key transcription factors will be explored employing a variety of advanced wet-lab techniques including conventional and single-cell RNA-sequencing and ChIP-seq, as well as biostatistics and bioinformatics analyses.
For more information and how to apply: https://www.jobbnorge.no/en/available-jobs/job/186304/researcher-in-immunogenetics
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