Postdoctoral Research Fellow in Yeast Integrative Multiomics

13th October 2023
Languages
English

• English

English
Postdoctoral Research Fellow in Yeast Integrative Multiomics
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About the position

Position as Postdoctoral Research Fellow available at Department of Biosciences, Faculty of Mathematics and Natural Sciences, University of Oslo.

The appointment is a fulltime position and is for a period of three years (10% of which is devoted to required duties, usually in the form of teaching activities).

No one can be appointed for more than one Postdoctoral Research Fellowship at the University of Oslo.

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Job description / Project description / Development plan:

The position will be affiliated with the Section for Genetics and Evolutionary Biology (EVO-GENE) with collaborators at the Centre for Ecological and Evolutionary Synthesis (CEES) at the Department of Biosciences, University of Oslo.

The post doc fellow will be working on the project “Effects of polyploidization during adaptive evolution in yeasts (PloidYeast)” lead by Dr. David Peris (PI) and funded by the Research Council of Norway (RCN 324253 ). The candidate will work in close collaboration with the PI, Dr. Sara Orellana, Dr. Inger Skrede, Prof. Håvard Kauserud, Oslo Mycology Group members (Postdoc, PhD and master students) and researchers at the Institute of Agrochemistry and Food Technology (IATA) –CSIC, Spain. In addition, the candidate will be part of an international collaborative research team from Stockholm University, Sweden (Dr. Rike Stelkens); Institute for Integrative Systems Biology (I2SysBio)-CSIC, Spain (Dr. Ana Conesa); Ghent University, Belgium (Dr. Yves Van de Peer); and Lawrence-Berkeley National Laboratory, USA (Dr. Héctor García). This research team provides an excellent scientific framework, with specialists in mycology, speciation, hybridization, food biotechnology, evolutionary biology, population genomics, multiomics integration and machine learning model applications.

Climatic change and human actions are threatening the sustainability of food security. United Nations has launched four aims within the sustainable development plan to maintain and ensure food security. In PloidYeast, we aim to apply a new collection of yeasts to offer new biotechnological approaches that can solve UN challenges, that is convert the food chain in a sustainable and a circular process. To accomplish this objective, we will make use of a recurrent evolutionary phenomenon observed in several industrial yeasts. This phenomenon is called polyploidization where the increase of the number of copies of the genome facilitates the adaptation to industrial conditions and might generate yeasts with desired industrial traits, accommodated to reach the sustainability of the food security. We will apply a multidisciplinary approach combining microbiology, molecular and genetic engineering methods, bioinformatics and mathematical modelling to generate the new yeasts and learn how polyploidization improves adaptation to industrial conditions. We know that increasing the number of copies in a yeast, by introducing the genome of multiple yeasts with different but desired industrial traits, generates a new yeast with the combination of the parental traits.

The post doc fellow will generate multiple omic layers (genomic, transcriptomic, proteomic, growth curves) of ancestral and evolved yeast polyploids in different media conditions. She/he will develop bioinformatic tools to integrate them by making use of machine learning techniques to infer the genomic regions associated with the phenomic regions related with the adaptation.

The post doctoral fellow is expected to perform at least one Research Stay Abroad (https://bit.ly/3EEcRk5 ) in any of the international collaborator lab mentioned above to expand the skills and knowledge related with the PloidYeast project aims and the postdoctoral career necessities.

The main purpose of a postdoctoral fellowship is to provide the candidates with enhanced skills to pursue a scientific top position within or beyond academia. To promote a strategic career path, all postdoctoral research fellows are required to submit a professional development plan no later than one month after commencement of the postdoctoral period.

It is expected that the successful candidate will be able to complete the project in the course of the period of employment.

Qualification requirements:

The Faculty of Mathematics and Natural Sciences has a strategic ambition to be among Europe’s leading communities for research, education and innovation. Candidates for these fellowships will be selected in accordance with this, and expected to be in the upper segment of their class with respect to academic credentials.

• Applicants must hold a degree equivalent to a Norwegian doctoral degree in in a field relevant for the project, including Genomics, Bioinformatics, Evolutionary Biology, Food Microbiology or similar. Doctoral dissertation must be submitted for evaluation by the closing date. Only applicants with an approved doctoral thesis and public defence are eligible for appointment.
• Knowledge in comparative genomics, population genomics and evolutionary biology
• Experience in bioinformatics applied to genomic data
• Fluent oral and written communication skills in English

Personal skills:

• A strong interest in fungal biology, fungal genomics, and bioinformatics
• Demonstrated ability in scientific writing and publications in relevant international scientific journals
• We seek a highly motivated, enthusiastic and hard-working candidate. Applicant must show good interpersonal skills and be willing to work in close collaboration with the project PI and other members of the international project team, as well as have the ability to work independently.

Personal suitability for the position will be emphasized.

Jarli og Jordan/UiO via Unsplash Jarli og Jordan/UiO
We offer:

• Salary NOK 575 400 – 657 300 per annum depending on qualifications in position as Postdoctoral Research Fellowship (position code 1352)
• Attractive welfare benefits and a generous pension agreement
• Professionally stimulating working environment
• Vibrant international academic environment
• Postdoctoral development programmes
• Oslo’s family-friendly surroundings with their rich opportunities for culture and outdoor activities

The application must include:

• Cover letter (statement of motivation, summarizing scientific work and research interest)
• A project description, emphasizing how the applicant will address different project challenges
• CV (summarizing education, positions, pedagogical experience, administrative experience and other qualifying activity)
• Copies of educational certificates, academic transcript of records
• A complete list of publications and up to 5 academic works that the applicant wishes to be considered by the evaluation committee
• Names and contact details of 2-3 references (name, relation to candidate, e-mail and telephone number)

The application with attachments must be delivered in our electronic recruiting system, please follow the link “apply for this job”. Foreign applicants are advised to attach an explanation of their University's grading system. Please note that all documents should be in English (or a Scandinavian language).

In assessing the applications, special emphasis will be placed on the documented, academic qualifications, as well as the candidates motivation and personal suitability. Interviews with the best qualified candidates will be arranged.

It is expected that the successful candidate will be able to complete the project in the course of the period of employment.

Formal regulations:

Please see the guidelines and regulations for appointments to Postdoctoral fellowships at the University of Oslo.

If an applicant has applied for and been granted funding for a fulltime research stay abroad while being employed as a Postdoctoral Research Fellow, the employment will be prolonged with the equivalent time as the research stay, but for no longer than of twelve months ( thus extending the employment to a maximum of four years)

No one can be appointed twice as a Postdoctoral fellow financed with funds from The Research Council of Norway (NFR).

According to the Norwegian Freedom and Information Act (Offentleglova) information about the applicant may be included in the public applicant list, also in cases where the applicant has requested non-disclosure.

The University of Oslo has an agreement for all employees , aiming to secure rights to research results a.o.

Inclusion and diversity are a strength. The University of Oslo has a personnel policy objective of achieving a balanced gender composition. Furthermore, we want employees with diverse professional expertise, life experience and perspectives.

If there are qualified applicants with disabilities, employment gaps or immigrant background, we will invite at least one applicant from each of these categories to an interview.

Contact persons:

For further information about the position please contact: David Peris, phone: +34 644 96 12 47, e-mail: david.perisnavarro@gmail.com

For questions regarding the recruitment system, please contact HR Adviser Nina Holtan, e-mail: nina.holtan@mn.uio.no

via Unsplash
About the University of Oslo

The University of Oslo is Norway’s oldest and highest rated institution of research and education with 28 000 students and 7000 employees. Its broad range of academic disciplines and internationally esteemed research communities make UiO an important contributor to society.

Department of Biosciences (IBV) is one of nine departments at the Faculty of Mathematics and Natural Sciences. Research in the department is organised in five sections covering topics within biochemistry, molecular biology, physiology, cell biology, genetics, aquatic biology, toxicology, ecology, and evolutionary biology. Education across these topics is offered for around 350 bachelor, 250 master, and 120 PhD students. With 52 permanent professors/associate professors, post-docs, researchers, technical, and administrative personnel, the Department has a total staff of 340 from more than 30 different countries. The Department aims to maintain high international standards within both research and teaching. The new bachelor program in bioscience is the first of its kind to include programming and computational modelling as core elements.

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Deadline

13th October 2023

Employer

University of Oslo

Municipality

Oslo

Scope

Fulltime (1 positions) Fulltime (%)

Duration

Project

Place of service
Problemveien 7, 0313 Oslo

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