The postdoc will take part in a basic project with strong clinical implications. The aim of the project is to identify new targets for improved treatment of B cell precursor acute lymphoblastic leukemia (BCP-ALL). A key feature of the project is modulation of the cAMP/PKA pathway in regulation of cellular processes such as DNA damage responses, oxidative stress, metabolism and autophagy. In addition to experiments on cell cultures of primary ALLs and ALL-derived cell lines, in vivo experiments on an established xenograft model of ALL in NSG mice will have a central role.
We are looking for candidates who have ample experience with cell culturing and assays related to DNA damage responses, metabolism, autophagy, and oxidative stress. It is essential that the candidate has experience with mice models and working in animal facilities.
For more information and how to apply: https://www.jobbnorge.no/en/available-jobs/job/218057/postdoctoral-research-fellow-in-biochemistry
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