Post-doctoral position - tumor microenvironment/inflammation

Our laboratory studies the contributions of the tumor microenvironment to therapy responses and metastasis. More specifically, our team focuses on inflammation and the functions of i) myeloid-derived immune cells, such as neutrophils and macrophages (Albrengues et al, Science, 2018), and; ii) fibroblasts (Albrengues et al, Cell Reports, 2014, Nature Communications 2015). Our laboratory is located at the Institute for Research on Cancer and Aging, Nice (IRCAN), in Nice, France, where multiple research teams focus of the cellular and molecular mechanism driving cancer progression and aging.

Our team studies the importance of tumor-stroma communications using co-culture assays and mouse models of breast cancer. We use co-culture assays to understand signaling pathways involved in communications between cancer cells and specific types of stromal cells (such as neutrophils, macrophages and fibroblasts). We combine these in vitro assays with mouse models to determine how interactions between cancer and stromal cells influence activation of signaling pathways and therefore cells survival, apoptosis, proliferation, invasion and metastasis.

The laboratory is currently seeking to hire an individual with a PhD in a relevant field, or interested in having a second post-doctoral position, with a strong interest in tumor-stroma. Candidates must be highly motivated, creative, dedicated to research and able to work independently as well as collaboratively. This full-time position is for 3 years, starting early 2022 (preferably March 2022) and it will be funded by the Agence Nationale de la Recherche (ANR). Ideally the successful candidate would have a strong track record in tumor biology and a deep understanding of the associated experimental methodologies. Experience with in vivo and 2D/3D in vitro models of cancer and/or inflammation would be an advantage.

Application Procedure.

Applicants should email the following to Jean Albrengues at [email protected]