Unravelling Plasma Membrane Structure in Response to Environmental Stimuli

Updated: 3 months ago
Deadline: 19 Feb 2024

18 Jan 2024
Job Information
Organisation/Company

Wageningen University & Research
Research Field

Physics
Researcher Profile

First Stage Researcher (R1)
Country

Netherlands
Application Deadline

19 Feb 2024 - 23:00 (UTC)
Type of Contract

Temporary
Job Status

Not Applicable
Hours Per Week

38.0
Is the job funded through the EU Research Framework Programme?

Not funded by an EU programme
Is the Job related to staff position within a Research Infrastructure?

No

Offer Description

Are you keen to unravel the physiology and molecular mechanisms responsible for plasma membrane adaptation to environmental stimuli? Are you looking to pursue a career in academia? We are looking for an inventive, creative and talented PhD student to join our team!

Much like the borders between countries, the plasma membrane (PM) functions as a natural boundary, delineating cellular constituents from their surroundings. Beyond its role as a protective barrier, the PM is instrumental in facilitating communication between cells and their external environment, positioning it as a pivotal site for studying this intricate interaction. Disturbances in the PM's function or composition have profound effects on cell survival, thereby adversely impacting the overall development and viability of plants. In our research group, our emphasis is on unraveling the intricate organization of the PM in response to various environmental cues. We strive to pinpoint both intrinsic and extrinsic membrane organizers crucial to these dynamic processes. To accomplish this, we employ plant-derived stress response peptides as a tool for our research.

The aim of the project is to characterize the spatio-temporal changes in plasma membrane proteome during the response to environmental stimuli focusing on the root of the model organism Arabidopsis thaliana. The project will focus on characterization of the dynamic changes in the PM proteome using various state-of-an-art approaches e.g. biochemistry, high-end confocal microscopy, spatial transcriptomics and cell biology.

Your responsibilities include the following:

  • Unravelling the changes in PM proteome using mass spectrometry.
  • Characterization of sub-domain organization of PM proteome using various microcopy techniques.
  • Identification of ubiquitination machinery involved in the PM proteome degradation process.
  • Establishment of the techniques as expansion microscopy and spatial transcriptomics.
  • Contributing to writing of peer-reviewed scientific manuscripts on the project results.
  • Participating in teaching of Cell Biology courses and supervising BSc and MSc thesis students.

You will work here
The research is embedded within the chair Cell and Developmental Biology (CBD) which is led by Prof. Viola Willemsen and ‘Grones group ’, a team within CBD led by Dr. Peter Grones. You will be co-supervised by Prof. Willemsen and Dr. Grones.


Requirements
Specific Requirements

We are looking for result-driven team player. We ask for:

  • an MSc degree in Plant Sciences, Molecular Biology or a related discipline;
  • experience with plant physiology, cell biology or biochemistry;
  • a collaborative mindset, with good communication skills;
  • excellent communication skills as well as good proficiency in English (both oral and written).

For this position your command of the English language is expected to be at C1 level . Sometimes it is necessary to submit an internationally recognized Certificate of Proficiency in the English Language. More information can be found here .


Additional Information
Benefits

Wageningen University & Research offers excellent terms of employment . A few highlights from our Collective Labour Agreement include:

  • Partially paid parental leave;
  • working hours that can be discussed and arranged so that they allow for the best possible work-life balance;
  • the option to accrue additional compensation / holiday hours by working more, up to 40 hours per week;
  • there is a strong focus on vitality and you can make use of the sports facilities available on campus for a small fee;
  • a fixed December bonus of 8.3%;
  • excellent pension scheme.

In addition to these first-rate employee benefits, you will receive a fully funded PhD position and you will be offered a course program tailored to your needs and the research team.
The gross salary for the first year is € 2.770 - per month rising to € 3.539,- in the fourth year in according to the Collective Labour Agreements for Dutch Universities (CAO-NU) (scale P). This is based on a full-time working week of 38 hours. We offer a temporary contract for 18 months which will be extended for the duration of the project if you perform well.

There are plenty of options for personal initiative in a learning environment, and we provide excellent training opportunities. We are offering a unique position in an international environment with a pleasant and open working atmosphere.

You are going to work at the greenest and most innovative campus in Holland, and at a university that has been chosen as the “Best University ” in the Netherlands for the 19th consecutive time.

Coming from abroad
Wageningen University & Research is the university and research centre for life sciences. The themes we deal with are relevant to everyone around the world and Wageningen, therefore, has a large international community and a lot to offer to international employees.

Our team of advisors on Dutch immigration procedures will help you with the visa application procedures for yourself and, if applicable, for your family.

Feeling welcome also has everything to do with being well informed. Wageningen University & Research's International Community page contains practical information about what we can do to support international employees and students coming to Wageningen. Furthermore, we can assist you with any additional advice and information about for example helping your partner to find a job, housing, or schooling. Finally, certain categories of international staff may be eligible for a tax exemption on a part of their salary during the first five years in the Netherlands.


Selection process

For more information about this position, please contact Dr. Peter Grones, by email:
[email protected]
For more information about the procedure, please contact Noorien Abbas, Corporate Recruiter, by email: [email protected]

Do you want to apply?
You can apply directly using the apply button on the vacancy page on our website which will allow us to process your personal information with your approval. Please submit a motivation letter, an updated CV, contacts on 2 referees and the mandatory form as mentioned below.

This vacancy will be listed up to and including 19 February 2024. We hope to schedule the first job interviews from 4 March 2024. The intended starting date will be from 1 June 2024.

Additional information form
For this position, you must fill in a mandatory form which will allow us to have a comprehensive view of your qualifications and better assess your fit for it. You can access the form using the link below:
https://forms.office.com/e/z7bCzMvmdf

Your prompt response will ensure that your application continues to move forward in the evaluation process. We assure you that the information provided will be kept confidential and used solely for this application process.

Equal opportunities
Wageningen University & Research (WUR) employs a large number of people with very different backgrounds and qualities, who inspire and motivate each other. We want every talent to feel at home in our organisation and be offered the same career opportunities. We therefore especially welcome applications from people who are underrepresented at WUR. A good example of how WUR deals with inclusiveness can be read on the page working at WUR with a functional impairment .


Additional comments

For more information about this position, please contact Dr. Peter Grones, by email:
[email protected]
For more information about the procedure, please contact Noorien Abbas, Corporate Recruiter, by email: [email protected]

Do you want to apply?
You can apply directly using the apply button on the vacancy page on our website which will allow us to process your personal information with your approval. Please submit a motivation letter, an updated CV, contacts on 2 referees and the mandatory form as mentioned below.

This vacancy will be listed up to and including 19 February 2024. We hope to schedule the first job interviews from 4 March 2024. The intended starting date will be from 1 June 2024.

Additional information form
For this position, you must fill in a mandatory form which will allow us to have a comprehensive view of your qualifications and better assess your fit for it. You can access the form using the link below:
https://forms.office.com/e/z7bCzMvmdf

Your prompt response will ensure that your application continues to move forward in the evaluation process. We assure you that the information provided will be kept confidential and used solely for this application process.

Equal opportunities
Wageningen University & Research (WUR) employs a large number of people with very different backgrounds and qualities, who inspire and motivate each other. We want every talent to feel at home in our organisation and be offered the same career opportunities. We therefore especially welcome applications from people who are underrepresented at WUR. A good example of how WUR deals with inclusiveness can be read on the page working at WUR with a functional impairment .


Website for additional job details

https://www.academictransfer.com/336705/

Work Location(s)
Number of offers available
1
Company/Institute
Wageningen University & Research
Country
Netherlands
City
Wageningen
Postal Code
6708 PB
Street
Droevendaalsesteeg
Geofield


Where to apply
Website

https://www.academictransfer.com/en/336705/unravelling-plasma-membrane-structur…

Contact
City

Wageningen
Website

http://www.wageningenur.nl
Street

Droevendaalsesteeg
Postal Code

6708 PB

STATUS: EXPIRED

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